An estimated 10–25% of lung cancers worldwide occur in never smokers, ie individuals
having smoked less than 100 cigarettes in their lifetime. Lung cancer in never smokers …

Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …

Lung cancer is the leading cause of cancer-related death in men and women in the United
States, accounting for approximately 28% of total cancer deaths in 2010 despite comprising …

Lung cancer, which has a low survival rate, is a leading cause of cancer-associated mortality
worldwide. Smoking and air pollution are the major causes of lung cancer; however …

More than 1000 candidate-gene association studies on genetic susceptibility to lung cancer
have been published over the last two decades but with few consensuses for the likely …

Lung cancer is the most common form of cancer death worldwide. Although reduction of
tobacco consumption remains the most appropriate strategy to reduce lung-cancer burden …

G protein–coupled receptors (GPCRs) play critical roles in regulating processes such as
cellular homeostasis, responses to stimuli, and cell signaling. Accordingly, GPCRs have …

Background Lung cancer in individuals who have never smoked tobacco products is an
increasing medical and public-health issue. We aimed to unravel the genetic basis of lung …

Genome-wide association studies have broadened our understanding of the genetic
architecture of cancer to include common variants, in addition to the rare variants previously …

Lung cancer is one of the most devastating diseases worldwide. RGS17 is previously shown
to be over-expressed in human lung adenocarcinomas and plays an important role in lung …