Precision medicine in fatty liver disease/non-alcoholic fatty liver disease

L Valenzuela-Vallejo, D Sanoudou… - Journal of Personalized …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease, and is
related to fatal and non-fatal liver, metabolic, and cardiovascular complications. Its non …

[HTML][HTML] Sarcopenia in chronic liver disease: a metabolic perspective

R Kumar, SS Prakash, RN Priyadarshi… - Journal of clinical and …, 2022 - ncbi.nlm.nih.gov
Sarcopenia, a condition of low muscle mass, quality, and strength, is commonly found in
patients with chronic liver disease (CLD) and is associated with adverse clinical outcomes …

Sarcopenia among patients with nonalcoholic fatty liver disease (NAFLD) is associated with advanced fibrosis

M Harring, P Golabi, JM Paik, D Shah, A Racila… - Clinical …, 2023 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) and sarcopenia can be
associated with advanced liver disease. Our aim was to assess the association between …

[HTML][HTML] Improving the prognosis before and after liver transplantation: Is muscle a game changer?

A Goffaux, A Delorme, G Dahlqvist… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Liver transplantation (LT) is currently the only curative treatment option for selected patients
with end stage liver disease or hepatocellular carcinoma. Improving waiting list-mortality …

Glucagon-like peptide-1 receptor agonist, semaglutide attenuates chronic liver disease-induced skeletal muscle atrophy in diabetic mice

S Iwai, K Kaji, N Nishimura, T Kubo, F Tomooka… - … et Biophysica Acta (BBA …, 2023 - Elsevier
A glucagon-like peptide-1 receptor agonist (GLP-1RA) has recently been established as a
pharmacological option for the treatment of type 2 diabetes. Recent studies have …

Ursodeoxycholic acid induces sarcopenia associated with decreased protein synthesis and autophagic flux

J Orozco-Aguilar, F Tacchi, F Aguirre… - Biological Research, 2023 - Springer
Background Skeletal muscle generates force and movements and maintains posture. Under
pathological conditions, muscle fibers suffer an imbalance in protein synthesis/degradation …

Association of lithocholic acid with skeletal muscle hypertrophy through TGR5-IGF-1 and skeletal muscle mass in cultured mouse myotubes, chronic liver disease rats …

Y Tamai, A Eguchi, R Shigefuku, H Kitamura… - Elife, 2022 - elifesciences.org
Background: Hepatic sarcopenia is one of many complications associated with chronic liver
disease (CLD) and has a high mortality rate; however, the liver-muscle axis is not fully …

Bronchial asthma and sarcopenia: an upcoming potential interaction

ND Karakousis, OS Kotsiou… - Journal of Personalized …, 2022 - mdpi.com
Background: Sarcopenia seems to be an emerging health issue worldwide, concerning the
progressive loss of skeletal muscle mass, accompanied by adverse outcomes. Asthma is a …

Psoas muscle index can be used to predict long-term mortality in young male patients with acute-on-chronic liver failure

M Xu, T Li, M Kong, N Geng, W Song, G Guo… - Frontiers in …, 2022 - frontiersin.org
Objective The use of psoas muscle index (PMI) in acute-on-chronic liver failure (ACLF) has
not been reported, and the aim of this study was to evaluate the predictive value of PMI for …

Sarcopenic obesity in people with alcoholic use disorder: relation with inflammation, vascular risk factors and serum Vitamin D levels

C Martín-González, P Fernández-Alonso… - International Journal of …, 2023 - mdpi.com
In recent years, the terms sarcopenia, sarcopenic obesity, and osteosarcopenic obesity
(OSO) were coined to define a situation in elderly people strongly associated with frailty and …