The recommendations listed in the present guideline are, whenever possible, evidence
based. An initial extensive evidence review, which included literature derived from research …

The American Heart Association requests that this document be cited as follows: Grundy SM,
Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, Braun LT, de Ferranti S, Faiella …

Deprescribing can be defined as the process of withdrawal or dose reduction of medications
which are considered inappropriate in an individual. The aim of this narrative review is to …

Importance Use of harmful and/or unnecessary medications in older adults is prevalent. This
can lead to avoidable harms such as adverse drug reactions, falls, hospitalization, and …

Background Harmful and/or unnecessary medication use in older adults is common. This
indicates deprescribing (supervised withdrawal of inappropriate medicines) is not …

Background Polypharmacy and potentially inappropriate medications (PIMs) are prevalent
in older adults in hospital, and are associated with negative outcomes including adverse …

Background Knowledge of consumer (patient and caregiver) attitudes is essential for
conducting medication optimization in practice. Objectives The aim of this study was to …

Background Deprescribing describes the complex process that is required for the safe and
effective cessation of medications that are likely to cause more harm than benefit …

Objectives Polypharmacy in the older population is increasing—and can be harmful. It can
be safe to reduce or carefully cease medicines (deprescribing) but a collaborative approach …

Introduction: There is increasing recognition of the need for deprescribing of inappropriate
medications in older adults. However, efforts to encourage implementation of deprescribing …