The bone marrow as sanctuary for plasma cells and memory T-cells: implications for adaptive immunity and vaccinology
SA Slamanig, MA Nolte - Cells, 2021 - mdpi.com
The bone marrow (BM) is key to protective immunological memory because it harbors a
major fraction of the body's plasma cells, memory CD4+ and memory CD8+ T-cells. Despite …
major fraction of the body's plasma cells, memory CD4+ and memory CD8+ T-cells. Despite …
[HTML][HTML] Blasts in context: the impact of the immune environment on acute myeloid leukemia prognosis and treatment
Acute myeloid leukemia (AML) is a cancer that originates from the bone marrow (BM). Under
physiological conditions, the bone marrow supports the homeostasis of immune cells and …
physiological conditions, the bone marrow supports the homeostasis of immune cells and …
[HTML][HTML] In vivo imaging of CD8+ T cells in metastatic cancer patients: first clinical experience with simultaneous [89Zr] Zr-Df-IAB22M2C PET/MRI
J Schwenck, D Sonanini, D Seyfried, W Ehrlichmann… - Theranostics, 2023 - ncbi.nlm.nih.gov
Aim/Introduction: Despite the spectacular success of immune checkpoint inhibitor therapy
(ICT) in patients with metastatic cancer, only a limited proportion of patients benefit from ICT …
(ICT) in patients with metastatic cancer, only a limited proportion of patients benefit from ICT …
Interactions of B-lymphocytes and bone cells in health and disease
Bone remodeling occurs through the interactions of three major cell lineages, osteoblasts,
which mediate bone formation, osteocytes, which derive from osteoblasts, sense mechanical …
which mediate bone formation, osteocytes, which derive from osteoblasts, sense mechanical …
Prevention effect of protopanaxadiol-type saponins saponins and protopanaxatriol-type saponins on myelosuppression mice induced by cyclophosphamide
H Zhang, L Zhang, C Yang, Y Zhang, J Li… - Frontiers in …, 2022 - frontiersin.org
Ginsenosides from ginseng are used as a therapeutic agent for various diseases. They
enhance the immunomodulatory effect in cyclophosphamide (CP)-treated tumor disease …
enhance the immunomodulatory effect in cyclophosphamide (CP)-treated tumor disease …
IL-9 secreted by leukemia stem cells induces Th1-skewed CD4+ T cells, which promote their expansion
In acute myeloid leukemia (AML), leukemia stem cells (LSCs) and leukemia progenitor cells
(LPCs) interact with various cell types in the bone marrow (BM) microenvironment …
(LPCs) interact with various cell types in the bone marrow (BM) microenvironment …
B cell/stromal cell crosstalk in health, disease, and treatment: Follicular lymphoma as a paradigm
C Lamaison, K Tarte - Immunological Reviews, 2021 - Wiley Online Library
Stromal cells organize specific anatomic compartments within bone marrow (BM) and
secondary lymphoid organs where they finely regulate the behavior of mature normal B …
secondary lymphoid organs where they finely regulate the behavior of mature normal B …
Three-dimensional human bone marrow organoids for the study and application of normal and abnormal hematoimmunopoiesis
A de Janon, A Mantalaris… - The Journal of …, 2023 - journals.aai.org
Hematoimmunopoiesis takes place in the adult human bone marrow (BM), which is
composed of heterogeneous niches with complex architecture that enables tight regulation …
composed of heterogeneous niches with complex architecture that enables tight regulation …
The dynamics of B‐cell reconstitution post allogeneic hematopoietic stem cell transplantation: A real‐world study
G Zhou, Q Zhan, L Huang, X Dou, J Cui… - Journal of Internal …, 2024 - Wiley Online Library
Background The immune reconstitution after allogeneic hematopoietic stem cell
transplantation (allo‐HSCT) is crucial for preventing infections and relapse and enhancing …
transplantation (allo‐HSCT) is crucial for preventing infections and relapse and enhancing …
Clinical characteristics of antithyroid drug-induced aplastic anemia cases over the past 30 years
Y Cheng, XY Xia, W Zhang, L Ren, CF Tian… - Frontiers in …, 2023 - frontiersin.org
Objective The authors aimed to investigate the clinical characteristics of antithyroid drug-
induced aplastic anemia cases over the past 30 years. Methods The data of patients with …
induced aplastic anemia cases over the past 30 years. Methods The data of patients with …