[HTML][HTML] Congenital aniridia beyond black eyes: from phenotype and novel genetic mechanisms to innovative therapeutic approaches
Congenital PAX6-aniridia, initially characterized by the absence of the iris, has progressively
been shown to be associated with other developmental ocular abnormalities and systemic …
been shown to be associated with other developmental ocular abnormalities and systemic …
Diabetic macular ischaemia-a new therapeutic target?
Diabetic macular ischaemia (DMI) is traditionally defined and graded based on the
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …
angiographic evidence of an enlarged and irregular foveal avascular zone. However, these …
A single‐cell transcriptome atlas of the adult human retina
The retina is a specialized neural tissue that senses light and initiates image processing.
Although the functional organization of specific retina cells has been well studied, the …
Although the functional organization of specific retina cells has been well studied, the …
Molecular anatomy of the developing human retina
Clinical and genetic heterogeneity associated with retinal diseases makes stem-cell-based
therapies an attractive strategy for personalized medicine. However, we have limited …
therapies an attractive strategy for personalized medicine. However, we have limited …
Adaptation of the central retina for high acuity vision: cones, the fovea and the avascular zone
Presence of a fovea centralis is directly linked to molecular specification of an avascular
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …
[HTML][HTML] The retinal pigmentation pathway in human albinism: Not so black and white
R Bakker, EL Wagstaff, CC Kruijt, E Emri… - Progress in retinal and …, 2022 - Elsevier
Albinism is a pigment disorder affecting eye, skin and/or hair. Patients usually have
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …
decreased melanin in affected tissues and suffer from severe visual abnormalities, including …
Histologic development of the human fovea from midgestation to maturity
A Hendrickson, D Possin, L Vajzovic, CA Toth - American journal of …, 2012 - Elsevier
PURPOSE: To describe the histologic development of the human central retina from fetal
week (Fwk) 22 to 13 years. DESIGN: Retrospective observational case series. METHODS …
week (Fwk) 22 to 13 years. DESIGN: Retrospective observational case series. METHODS …
Retinal vascular layers in macular telangiectasia type 2 imaged by optical coherence tomographic angiography
RF Spaide, JM Klancnik, MJ Cooney - JAMA ophthalmology, 2015 - jamanetwork.com
Importance Macular telangiectasia type 2 (MacTel 2) is a rare disease in which
abnormalities of the retinal vasculature play a key role. The vascular abnormalities are …
abnormalities of the retinal vasculature play a key role. The vascular abnormalities are …
Pathophysiology, screening and treatment of ROP: a multi-disciplinary perspective
The population of infants at risk for retinopathy of prematurity (ROP) varies by world region;
in countries with well developed neonatal intensive care services, the highest risk infants are …
in countries with well developed neonatal intensive care services, the highest risk infants are …
Development of the hyaloid, choroidal and retinal vasculatures in the fetal human eye
The development of the ocular vasculatures is perfectly synchronized to provide the
nutritional and oxygen requirements of the forming human eye. The fetal vasculature of …
nutritional and oxygen requirements of the forming human eye. The fetal vasculature of …