The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
rapid international spread has caused the coronavirus disease 2019 (COVID-19) …

Malignant glioma, which is characterized by diffuse infiltration into the normal brain
parenchyma, is the most aggressive primary brain tumor with dismal prognosis. Over the …

The human induced pluripotent stem cell (hiPSC) provides a breakthrough approach that
helps overcoming ethical and allergenic challenges posed in application of neural stem …

Background Neoadjuvant chemotherapy (NAC) induces a pathological complete response
(pCR) in~ 30% of patients with breast cancer. However, aberrant DNA methylation …

The human induced pluripotent stem cell (iPSC) technique promises to provide an unlimited,
reliable source of genetically matched pluripotent cells for personalized therapy and disease …

Recently, the clustered regularly interspaced short palindromic repeats (CRISPR) system
has emerged as a powerful customizable artificial nuclease to facilitate precise genetic …

Cell‑cell fusion is a dynamic biological phenomenon, which plays an important role in
various physiological processes, such as tissue regeneration. Similarly, normal cells …

Glioma is the most common malignant brain tumor, and the incidence of glioma
demonstrates an upward trend. It is vital to elucidate the pathogenesis of glioma and seek …

In addition to DNA methylation and chromatin structure, another important level of epigenetic
regulation for gene expression is non-coding RNA (ncRNA)(Luo et al., 2019). NcRNAs …

The yeasts, including Saccharomyces cerevisiae and Pichia pastoris, are single‐cell
eukaryotic organisms that can serve as models for human genetic diseases and hosts for …