Basic mechanisms of hemolysis-associated thrombo-inflammation and immune dysregulation

JD Dimitrov, LT Roumenina, G Perrella… - … , and Vascular Biology, 2023 - Am Heart Assoc
Independent of etiology, hemolytic diseases are associated with thrombosis, inflammation
and immune dysregulation, all together contributing to organ damage and poor outcome …

Neutrophils extracellular traps and ferroptosis in diabetic wounds

Y Huang, Y Ding, B Wang, Q Ji… - International wound …, 2023 - Wiley Online Library
Wound healing is an extremely complex process involving multiple levels of cells and
tissues. It is mainly completed through four stages: haemostasis, inflammation, proliferation …

The magic of proteases: from a procoagulant and anticoagulant factor V to an equitable treatment of its inherited deficiency

JA De Pablo-Moreno, A Miguel-Batuecas… - International Journal of …, 2023 - mdpi.com
Proteostasis, ie, the homeostasis of proteins, responsible for ensuring protein turnover, is
regulated by proteases, which also participate in the etiopathogenesis of multiple conditions …

cGMP modulates hemin-mediated platelet death

AK Rohlfing, M Kremser, D Schaale… - Thrombosis …, 2024 - Elsevier
Background and aims Hemolysis is a known risk factor for thrombosis resulting in critical
limb ischemia and microcirculatory disturbance and organ failure. Intravasal hemolysis may …

The crosstalk between mitochondrial quality control and metal-dependent cell death

Q Zhou, C Ren, J Li, L Wang, Y Duan, R Yao… - Cell Death & …, 2024 - nature.com
Mitochondria are the centers of energy and material metabolism, and they also serve as the
storage and dispatch hubs of metal ions. Damage to mitochondrial structure and function …

The convergent model of coagulation

J Yong, CH Toh - Journal of Thrombosis and Haemostasis, 2024 - Elsevier
It is increasingly apparent that the pathological interplay between coagulation and innate
immunity, ie immunothrombosis, forms the common basis of many challenges across the …

Neutrophil extracellular trap-induced ferroptosis promotes abdominal aortic aneurysm formation via SLC25A11-mediated depletion of mitochondrial glutathione

Y Qi, L Chen, S Ding, X Shen, Z Wang, H Qi… - Free Radical Biology and …, 2024 - Elsevier
Abstract Background Neutrophil extracellular traps (NETs) induce oxidative stress, which
may initiate ferroptosis, an iron-dependent programmed cell death, during abdominal aortic …

Neutrophil extracellular traps: molecular and cellular mechanisms of formation, role in the development of placental disorders and preeclampsia

SA Gasparyan, AG Topuzov, IA Orfanova… - Almanac of Clinical …, 2023 - almclinmed.ru
The review summarizes current understanding of neutrophil extracellular traps (NETs) and
their role in the development of inflammation and thrombus formation during physiological …

[HTML][HTML] Нейтрофильные внеклеточные ловушки: молекулярно-клеточные механизмы формирования, роль в развитии плацентарных нарушений и …

СА Гаспарян, АГ Топузов, ИА Орфанова… - Альманах …, 2023 - cyberleninka.ru
В обзоре обобщены современные представления о нейтрофильных внеклеточных
ловушках (англ. neutrophil extracellular traps, NETs) и их роли в развитии процессов …