The implications of exosomes in pregnancy: emerging as new diagnostic markers and therapeutics targets

M Ghafourian, R Mahdavi, Z Akbari Jonoush… - Cell Communication and …, 2022 - Springer
Extracellular vehicles (EVs) are a heterogeneous group of cell and membranous particles
originating from different cell compartments. EVs participate in many essential physiological …

Extracellular vesicles in atherothrombosis: From biomarkers and precision medicine to therapeutic targets

L Badimon, T Padro, G Arderiu, G Vilahur… - Immunological …, 2022 - Wiley Online Library
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of global
mortality. Extracellular vesicles (EVs) are small phospholipid vesicles that convey molecular …

Maternal HPV infection: Effects on pregnancy outcome

CE Condrat, L Filip, M Gherghe, D Cretoiu, N Suciu - Viruses, 2021 - mdpi.com
The human papilloma virus (HPV) infection, caused by a ubiquitous virus typically
transmitted through the direct contact of infected organs, either through the skin or mucosa …

Extracellular vesicles as drivers of immunoinflammation in atherothrombosis

R Suades, MF Greco, T Padró, L Badimon - Cells, 2022 - mdpi.com
Atherosclerotic cardiovascular disease is the leading cause of morbidity and mortality all
over the world. Extracellular vesicles (EVs), small lipid-bilayer membrane vesicles released …

Environmental nanoparticles reach human fetal brains

L Calderón-Garcidueñas, ÁA Pérez-Calatayud… - Biomedicines, 2022 - mdpi.com
Anthropogenic ultrafine particulate matter (UFPM) and industrial and natural nanoparticles
(NPs) are ubiquitous. Normal term, preeclamptic, and postconceptional weeks (PCW) 8–15 …

Unfolding the role of placental-derived Extracellular Vesicles in Pregnancy: From homeostasis to pathophysiology

MA Ortega, O Fraile-Martínez… - Frontiers in Cell and …, 2022 - frontiersin.org
The human placenta is a critical structure with multiple roles in pregnancy, including fetal
nutrition and support, immunological, mechanical and chemical barrier as well as an …

[HTML][HTML] Inflammation and oxidative stress as mediators of the impacts of environmental exposures on human pregnancy: Evidence from oxylipins

BM Welch, EE McNell, ML Edin, KK Ferguson - Pharmacology & …, 2022 - Elsevier
Inflammation and oxidative stress play major roles in healthy and pathological pregnancy.
Environmental exposure to chemical pollutants may adversely affect maternal and fetal …

Confirming size-exclusion chromatography as a clinically relevant extracellular vesicles separation method from 1mL plasma through a comprehensive comparison of …

SD Robinson, M Samuels, W Jones, N Stewart… - BMC Methods, 2024 - Springer
Abstract Background Extracellular vesicles (EVs) are amongst the most promising
candidates for developing blood-based biomarkers. However, patient sample availability is …

The role of non-coding RNAs in the human placenta

M Žarković, F Hufsky, UR Markert, M Marz - Cells, 2022 - mdpi.com
Non-coding RNAs (ncRNAs) play a central and regulatory role in almost all cells, organs,
and species, which has been broadly recognized since the human ENCODE project and …

Advances in extracellular vesicles as mediators of cell-to-cell communication in pregnancy

S Nair, M Razo-Azamar, N Jayabalan… - Cytokine & Growth …, 2023 - Elsevier
Cell-to-cell communication mediated by Extracellular Vesicles (EVs) is a novel and
emerging area of research, especially during pregnancy, in which placenta derived EVs can …