Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Asialoglycoprotein receptor mediated hepatocyte targeting—Strategies and applications

AA D'Souza, PV Devarajan - Journal of controlled release, 2015 - Elsevier
Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …

Carbohydrates in supramolecular chemistry

M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …

Multifunctional biomedical materials derived from biological membranes

Y Wang, X Xu, X Chen, J Li - Advanced Materials, 2022 - Wiley Online Library
The delicate structure and fantastic functions of biological membranes are the successful
evolutionary results of a long‐term natural selection process. Their excellent biocompatibility …

Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents

T Mosaiab, DC Farr, MJ Kiefel, TA Houston - Advanced drug delivery …, 2019 - Elsevier
Many deadly infections are produced by microorganisms capable of sustained survival in
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …

Sugar-breathing glycopolymersomes for regulating glucose level

Y Xiao, H Sun, J Du - Journal of the American Chemical Society, 2017 - ACS Publications
Diabetes mellitus is a chronic, life-threatening illness that affects people of every age and
ethnicity. It is a long-term pain for those who are affected and must regulate their blood …

Highly sensitive imaging of tumor metastasis based on the targeting and polarization of M2-like macrophages

P Yuan, X Xu, D Hu, Y Chen, J Fan, S Yao… - Journal of the …, 2023 - ACS Publications
Tumor-associated macrophages, especially M2-like macrophages, are extensively involved
in tumor growth and metastasis, suppressing the innate immunity to help tumor cells escape …

Bio‐Conjugated Advanced Materials for Targeted Disease Theranostics

XL Hu, N Kwon, KC Yan, AC Sedgwick… - Advanced Functional …, 2020 - Wiley Online Library
Human beings are “machines” that use endogenously produced biomolecules as
“components” in signaling and for the maintenance of the body. These biomolecules consist …

Fluorescent glycoconjugates and their applications

B Thomas, KC Yan, XL Hu… - Chemical Society …, 2020 - pubs.rsc.org
Glycoconjugates and their applications as lectin ligands in biology have been thoroughly
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …

Glycocalyx‐mimicking nanoparticles for stimulation and polarization of macrophages via specific interactions

L Su, W Zhang, X Wu, Y Zhang, X Chen, G Liu, G Chen… - Small, 2015 - Wiley Online Library
Malignant tumors develop multiple mechanisms to impair and escape from antitumor
immune responses, of which tumor‐associated macrophages that often show …