Carbohydrate-based macromolecular biomaterials
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …
Asialoglycoprotein receptor mediated hepatocyte targeting—Strategies and applications
AA D'Souza, PV Devarajan - Journal of controlled release, 2015 - Elsevier
Hepatocyte resident afflictions continue to affect the human population unabated. The
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …
asialoglycoprotein receptor (ASGPR) is primarily expressed on hepatocytes and minimally …
Carbohydrates in supramolecular chemistry
M Delbianco, P Bharate, S Varela-Aramburu… - Chemical …, 2016 - ACS Publications
Carbohydrates are involved in a variety of biological processes. The ability of sugars to form
a large number of hydrogen bonds has made them important components for …
a large number of hydrogen bonds has made them important components for …
Multifunctional biomedical materials derived from biological membranes
Y Wang, X Xu, X Chen, J Li - Advanced Materials, 2022 - Wiley Online Library
The delicate structure and fantastic functions of biological membranes are the successful
evolutionary results of a long‐term natural selection process. Their excellent biocompatibility …
evolutionary results of a long‐term natural selection process. Their excellent biocompatibility …
Carbohydrate-based nanocarriers and their application to target macrophages and deliver antimicrobial agents
Many deadly infections are produced by microorganisms capable of sustained survival in
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …
macrophages. This reduces exposure to chemadrotherapy, prevents immune detection, and …
Sugar-breathing glycopolymersomes for regulating glucose level
Diabetes mellitus is a chronic, life-threatening illness that affects people of every age and
ethnicity. It is a long-term pain for those who are affected and must regulate their blood …
ethnicity. It is a long-term pain for those who are affected and must regulate their blood …
Highly sensitive imaging of tumor metastasis based on the targeting and polarization of M2-like macrophages
P Yuan, X Xu, D Hu, Y Chen, J Fan, S Yao… - Journal of the …, 2023 - ACS Publications
Tumor-associated macrophages, especially M2-like macrophages, are extensively involved
in tumor growth and metastasis, suppressing the innate immunity to help tumor cells escape …
in tumor growth and metastasis, suppressing the innate immunity to help tumor cells escape …
Bio‐Conjugated Advanced Materials for Targeted Disease Theranostics
XL Hu, N Kwon, KC Yan, AC Sedgwick… - Advanced Functional …, 2020 - Wiley Online Library
Human beings are “machines” that use endogenously produced biomolecules as
“components” in signaling and for the maintenance of the body. These biomolecules consist …
“components” in signaling and for the maintenance of the body. These biomolecules consist …
Fluorescent glycoconjugates and their applications
B Thomas, KC Yan, XL Hu… - Chemical Society …, 2020 - pubs.rsc.org
Glycoconjugates and their applications as lectin ligands in biology have been thoroughly
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …
investigated in the past decades. Meanwhile, the intrinsic properties of such multivalent …
Glycocalyx‐mimicking nanoparticles for stimulation and polarization of macrophages via specific interactions
Malignant tumors develop multiple mechanisms to impair and escape from antitumor
immune responses, of which tumor‐associated macrophages that often show …
immune responses, of which tumor‐associated macrophages that often show …