Mitochondria are a major target in hypoxic/ischemic injury. Mitochondrial impairment
increases with age leading to dysregulation of molecular pathways linked to mitochondria …

Free radical induced neural damage is implicated in cerebral ischemia–reperfusion (IR)
injury and antioxidants are reported to have neuroprotective activity. The present study was …

Mammalian adult central nerve system (CNS) injuries are devastating because of the
intrinsic difficulties for effective neuronal regeneration. The greatest problem to be overcome …

Stroke leads to brain damage with subsequent slow and incomplete recovery of lost brain
functions. Enriched housing of stroke-injured rats provides multi-modal sensorimotor …

The nucleotide oligomerization domain (NOD)-like receptor (NLR) pyrin domain-containing
protein 1 (NLRP1) inflammasome has been shown to contribute to brain injury after ischemic …

Functional recovery after cortical injury, such as stroke, is associated with neural circuit
reorganization, but the underlying mechanisms and efficacy of therapeutic interventions …

Background Vasogenic brain edema is the most important complication of ischemic stroke
that aggravates primary brain injury. Ischemia-Reperfusion (IR)-induced Blood-Brain Barrier …

Progressive age-associated increases in cerebral dysfunction have been shown to occur
following traumatic brain injury (TBI). Moreover, levels of neuronal mitochondrial antioxidant …

Ethanol is known as an effective agent against cerebral lesions after ischemia. Modafinil is a
stimulant of the central nervous system (CNS) with antioxidant properties. We assessed the …

Identification of functional molecules in the brain related to improvement of the degree of
paralysis or increase of activities will contribute to establishing a new treatment strategy for …