Liposomes as nanomedical devices

G Bozzuto, A Molinari - International journal of nanomedicine, 2015 - Taylor & Francis
Since their discovery in the 1960s, liposomes have been studied in depth, and they continue
to constitute a field of intense research. Liposomes are valued for their biological and …

Immunological and toxicological considerations for the design of liposomes

CT Inglut, AJ Sorrin, T Kuruppu, S Vig, J Cicalo… - Nanomaterials, 2020 - mdpi.com
Liposomes hold great potential as gene and drug delivery vehicles due to their
biocompatibility and modular properties, coupled with the major advantage of attenuating …

Nanodiscs in membrane biochemistry and biophysics

IG Denisov, SG Sligar - Chemical reviews, 2017 - ACS Publications
Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Pharmaceutical liposomal drug delivery: a review of new delivery systems and a look at the regulatory landscape

C Zylberberg, S Matosevic - Drug delivery, 2016 - Taylor & Francis
Liposomes were the first nanoscale drug to be approved for clinical use in 1995. Since then,
the technology has grown considerably, and pioneering recent work in liposome-based …

Natural product-based nanomedicine: recent advances and issues

R Watkins, L Wu, C Zhang, RM Davis… - International journal of …, 2015 - Taylor & Francis
Natural products have been used in medicine for many years. Many top-selling
pharmaceuticals are natural compounds or their derivatives. These plant-or microorganism …

Liposomes: clinical applications and potential for image-guided drug delivery

N Lamichhane, TS Udayakumar, WD D'Souza… - Molecules, 2018 - mdpi.com
Liposomes have been extensively studied and are used in the treatment of several
diseases. Liposomes improve the therapeutic efficacy by enhancing drug absorption while …

Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy

HI Chang, MK Yeh - International journal of nanomedicine, 2012 - Taylor & Francis
Research on liposome formulations has progressed from that on conventional vesicles to
new generation liposomes, such as cationic liposomes, temperature sensitive liposomes …

Nanocarrier‐mediated cytosolic delivery of biopharmaceuticals

W He, X Xing, X Wang, D Wu, W Wu… - Advanced functional …, 2020 - Wiley Online Library
Biopharmaceuticals have emerged to play a vital role in disease treatment and have shown
promise in the rapidly expanding pharmaceutical market due to their high specificity and …

Drug delivery strategies for poorly water-soluble drugs

A Fahr, X Liu - Expert opinion on drug delivery, 2007 - Taylor & Francis
The drug candidates coming from combinatorial chemistry research and/or the drugs
selected from biologically based high-throughput screening are quite often very lipophilic, as …

Sustained-release from nanocarriers: a review

JV Natarajan, C Nugraha, XW Ng… - Journal of Controlled …, 2014 - Elsevier
Nanocarriers have been explored for delivering drugs and other bioactive molecules for well
over 35 years. Since the introduction of Doxil®, a nanoliposomal delivery system for the …