Self-nano-emulsifying drug-delivery systems: From the development to the current applications and challenges in oral drug delivery

AB Buya, A Beloqui, PB Memvanga, V Préat - Pharmaceutics, 2020 - mdpi.com
Approximately one third of newly discovered drug molecules show insufficient water
solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Solid self emulsifying drug delivery system: Superior mode for oral delivery of hydrophobic cargos

I Maji, S Mahajan, A Sriram, P Medtiya… - Journal of Controlled …, 2021 - Elsevier
A significant proportion of recently approved drug molecules possess poor aqueous
solubility which further restrains their desired bioavailability. Poor aqueous solubility of these …

Formulation strategies to improve the bioavailability of poorly absorbed drugs with special emphasis on self‐emulsifying systems

S Gupta, R Kesarla, A Omri - International Scholarly Research …, 2013 - Wiley Online Library
Poorly water‐soluble drug candidates are becoming more prevalent. It has been estimated
that approximately 60–70% of the drug molecules are insufficiently soluble in aqueous …

Lipid based nanocarriers: a translational perspective

DK Mishra, R Shandilya, PK Mishra - … : Nanotechnology, Biology and …, 2018 - Elsevier
Over the recent couple of decades, pharmaceutical field has embarked most phenomenal
noteworthy achievements in the field of medications as well as drug delivery. The rise of …

Nanoemulsion delivery systems for enhanced efficacy of antimicrobials and essential oils

CR Garcia, MH Malik, S Biswas, VH Tam… - Biomaterials …, 2022 - pubs.rsc.org
The ever-growing threat of new and existing infectious diseases in combination with
antimicrobial resistance requires the need for innovative and effective forms of drug delivery …

Self-nanoemulsifying drug delivery system for pancreatic cancer

N Parveen, A Sheikh, MAS Abourehab… - European Polymer …, 2023 - Elsevier
Pancreatic cancer is the world's fourth largest causative factor of mortality with a five year of
survival rate. Poor definitive diagnosis can be ascribed to both problematic early detections …

From nanoemulsions to self-nanoemulsions, with recent advances in self-nanoemulsifying drug delivery systems (SNEDDS)

FU Rehman, KU Shah, SU Shah, IU Khan… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Lipid-based drug delivery systems (LBDDS) are the most promising technique
to formulate the poorly water soluble drugs. Nanotechnology strongly influences the …