Sex differences in lifespan are well recognized in the majority of animal species. For
example, in male versus female Drosophila melanogaster there are significant differences in …

The spatio-temporal regulation of gene expression determines the fate and function of
various cells and tissues and, as a consequence, the correct development and functioning of …

ABSTRACT A characteristic of normal aging and age-related diseases is the remodeling of
the cellular organization of a tissue through polyploid cell growth. Polyploidy arises from an …

Highlights•Unmated male black soldier flies live longer than unmated females.•Mating
reduces the longevity difference between unmated males and females.•The transparent …

The precise regulation of metabolism and feeding behavior is important for preventing the
development of metabolic diseases. Here we examine the effects on Drosophila metabolism …

During recent decades, model organisms such as Drosophila melanogaster have made it
possible to study the effects of different environmental oxygen conditions on lifespan and …

HE is a natural extract with strong antioxidant capacity. Drosophila melanogaster was used
to explore HE could delay aging in this study. We detected that 3 mg/ml HE could increase …

Macronutrient intake impacts physiology, behavior, and gene expression in a wide range of
organisms. We used the response surface methodology to compare how life history traits …

Aging is associated with decreased nitric oxide (NO) bioavailability and signalling. Boosting
of a dietary nitrate-nitrite-NO pathway eg by ingestion of leafy green vegetables, improves …

The neuronal mechanisms by which complex behaviors are coordinated and timed often
involve neuropeptidergic regulation of stress and reward pathways. Recent studies of the …