New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?

A Fardet - Nutrition research reviews, 2010 - cambridge.org
Epidemiological studies have clearly shown that whole-grain cereals can protect against
obesity, diabetes, CVD and cancers. The specific effects of food structure (increased satiety …

n-3 fatty acids, inflammation and immunity: new mechanisms to explain old actions

PC Calder - Proceedings of the Nutrition Society, 2013 - cambridge.org
Numerous effects of n-3 fatty acids EPA and DHA on functional responses of cells involved
in inflammation and immunity have been described. Fatty acid-induced modifications in …

Linoleic acid: A narrative review of the effects of increased intake in the standard american diet and associations with chronic disease

J Mercola, CR D'Adamo - Nutrients, 2023 - mdpi.com
The intake of linoleic acid (LA) has increased dramatically in the standard American diet. LA
is generally promoted as supporting human health, but there exists controversy regarding …

[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers

R Mallick, S Basak, AK Duttaroy - Progress in lipid research, 2021 - Elsevier
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

Arachidonic acid-metabolizing cytochrome P450 enzymes are targets of ω-3 fatty acids

C Arnold, M Markovic, K Blossey, G Wallukat… - Journal of Biological …, 2010 - ASBMB
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) protect against
cardiovascular disease by largely unknown mechanisms. We tested the hypothesis that EPA …

Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway [S]

R Fischer, A Konkel, H Mehling, K Blossey… - Journal of lipid …, 2014 - ASBMB
Cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA) contribute to the
regulation of cardiovascular function. CYP enzymes also accept EPA and DHA to yield more …

An Ultrasmall Cu/Cu2O Nanoparticle-Based Diselenide-Bridged Nanoplatform Mediating Reactive Oxygen Species Scavenging and Neuronal Membrane …

J Kong, R Zou, R Chu, N Hu, J Liu, Y Sun, X Ge… - ACS …, 2023 - ACS Publications
Ischemic stroke is one of the major causes of death and disability worldwide, and an
effective and timely treatment of ischemic stroke has been a challenge because of the …

Role of cytochrome P450 enzymes in the bioactivation of polyunsaturated fatty acids

A Konkel, WH Schunck - Biochimica et Biophysica Acta (BBA)-Proteins and …, 2011 - Elsevier
Cytochrome P450 (CYP)-dependent metabolites of arachidonic acid (AA), such as
epoxyeicosatrienoic acids and 20-hydroxyeicosatetraenoic acid, serve as second …

Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids

HF Turk, RS Chapkin - Prostaglandins, Leukotrienes and Essential Fatty …, 2013 - Elsevier
Fish oil, enriched in bioactive n-3 polyunsaturated fatty acids (PUFA), has been shown to
play a role in prevention of colon cancer. The effects of n-3 PUFA are pleiotropic and …

[PDF][PDF] FATTY ACIDS AS BIOCOMPOUNDS: THEIR ROLE IN HUMAN METABOLISM, HEALTH AND DISEASE-A REVIEW. PART 2: FATTY ACID PHYSIOLOGICAL …

LS Kremmyda, E Tvrzicka… - Biomedical Papers of …, 2011 - biomed.papers.upol.cz
Background. This is the second of two review parts aiming at describing the major
physiological roles of fatty acids, as well as their applications in specific conditions related to …