Organisms are continually exposed to exogenous and endogenous sources of reactive
oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects …

Ferroptosis, a programmed cell death, has been identified and associated with cancer and
various other diseases. Ferroptosis is defined as a reactive oxygen species (ROS) …

Cancer cells undergo metabolic alterations to meet the immense demand for energy,
building blocks, and redox potential. Tumors show glucose-avid and lactate-secreting …

Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Autophagy is an intracellular catabolic pathway in which cellular constituents are engulfed
by autophagosomes and degraded upon autophagosome fusion with lysosomes …

Autophagy influences cell survival through maintenance of cell bioenergetics and clearance
of protein aggregates and damaged organelles. Several lines of evidence indicate that …

Preeclampsia is a persistent hypertensive gestational disease characterized by high blood
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …

Reactive oxygen species (ROS), a group of highly reactive ions and molecules, are
increasingly being appreciated as powerful signaling molecules involved in the regulation of …

Macroautophagy (hereafter referred to as “autophagy”) is a lysosome-mediated degradation
process that plays a complex role in cellular stress, either promoting survival or triggering …

Copper oxide nanoparticles (CuO NPs) use has exponentially increased in various
applications (such as industrial catalyst, gas sensors, electronic materials, biomedicines …