Eco-evolutionary causes and consequences of temporal changes in intratumoural blood flow

RJ Gillies, JS Brown, ARA Anderson… - Nature Reviews …, 2018 - nature.com
Temporal changes in blood flow are commonly observed in malignant tumours, but the
evolutionary causes and consequences are rarely considered. We propose that stochastic …

[HTML][HTML] Development of copper based drugs, radiopharmaceuticals and medical materials

P Szymański, T Frączek, M Markowicz… - Biometals, 2012 - Springer
Copper is one of the most interesting elements for various biomedical applications. Copper
compounds show vast array of biological actions, including anti-inflammatory, anti …

A practical guide to the construction of radiometallated bioconjugates for positron emission tomography

BM Zeglis, JS Lewis - Dalton Transactions, 2011 - pubs.rsc.org
Positron emission tomography (PET) has become a vital imaging modality in the diagnosis
and treatment of disease, most notably cancer. A wide array of small molecule PET …

Metal complexes of thiosemicarbazones for imaging and therapy

JR Dilworth, R Hueting - Inorganica Chimica Acta, 2012 - Elsevier
This review gives an account of the coordination chemistry of thiosemicarbazone ligands
with three (tridentate) or four (tetradentate) potential donor atoms. The syntheses and …

Initial results of hypoxia imaging using 1-α-d-(5-deoxy-5-[18F]-fluoroarabinofuranosyl)-2-nitroimidazole (18F-FAZA)

EJ Postema, AJB McEwan, TA Riauka, P Kumar… - European journal of …, 2009 - Springer
Purpose Tumour hypoxia is thought to play a significant role in the outcome of solid tumour
therapy. Positron emission tomography (PET) is the best-validated noninvasive technique …

Copper radiopharmaceuticals for theranostic applications

A Ahmedova, B Todorov, N Burdzhiev… - European Journal of …, 2018 - Elsevier
The growing advancement in nuclear medicine challenges researchers from several
different fields to integrate imaging and therapeutic modalities in a theranostic …

[HTML][HTML] Radionuclide generators: the prospect of availing PET radiotracers to meet current clinical needs and future research demands

A Dash, R Chakravarty - American journal of nuclear medicine and …, 2019 - ncbi.nlm.nih.gov
Targeted molecular imaging with positron emission tomography (PET) constitutes a
successful technique for detecting and diagnosing disease conditions promptly and …

Copper, gallium and zirconium positron emission tomography imaging agents: The importance of metal ion speciation

LE McInnes, SE Rudd, PS Donnelly - Coordination Chemistry Reviews, 2017 - Elsevier
Positron emission tomography (PET) is a medical diagnostic imaging technique that
requires administration of a β+-emitting radiotracer to a patient. Metal-based PET …

[HTML][HTML] Local failure patterns for patients with nasopharyngeal carcinoma after intensity-modulated radiotherapy

J Li, S Huang, X Jiang, B Ouyang, F Han, S Liu… - Radiation …, 2014 - Springer
Background To investigate the clinical feature and the local failure patterns after intensity-
modulated radiotherapy for nasopharyngeal carcinoma. Methods Between March 2007 and …

Molecular PET/CT imaging-guided radiation therapy treatment planning

H Zaidi, H Vees, M Wissmeyer - Academic Radiology, 2009 - Elsevier
The role of positron emission tomography (PET) during the past decade has evolved rapidly
from that of a pure research tool to a methodology of enormous clinical potential. 18F …