[HTML][HTML] A systematic approach to quantitative Western blot analysis

L Pillai-Kastoori, AR Schutz-Geschwender… - Analytical …, 2020 - Elsevier
Attaining true quantitative data from WB requires that all the players involved in the
procedure are quality controlled including the user. Appropriate protein extraction method …

Hepatectomy-induced alterations in hepatic perfusion and function-toward multi-scale computational modeling for a better prediction of post-hepatectomy liver function

B Christ, M Collatz, U Dahmen, KH Herrmann… - Frontiers in …, 2021 - frontiersin.org
Liver resection causes marked perfusion alterations in the liver remnant both on the organ
scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level) …

DNAJC6 Mutations Associated With Early‐Onset Parkinson's Disease

S Olgiati, M Quadri, M Fang, JPMA Rood… - Annals of …, 2016 - Wiley Online Library
Objective DNAJC6 mutations were recently described in two families with autosomal
recessive juvenile parkinsonism (onset age< 11), prominent atypical signs, poor or absent …

Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior

M Bijata, E Bączyńska, FE Müller, K Bijata, J Masternak… - Cell Reports, 2022 - cell.com
Major depressive disorder is a complex disease resulting from aberrant synaptic plasticity
that may be caused by abnormal serotonergic signaling. Using a combination of behavioral …

BDNF-dependent modulation of axonal transport is selectively impaired in ALS

AP Tosolini, JN Sleigh, S Surana, ER Rhymes… - Acta Neuropathologica …, 2022 - Springer
Axonal transport ensures long-range delivery of essential cargoes between proximal and
distal compartments, and is needed for neuronal development, function, and survival …

Resveratrol preconditioning protects against cerebral ischemic injury via nuclear erythroid 2–related factor 2

SV Narayanan, KR Dave, I Saul, MA Perez-Pinzon - Stroke, 2015 - Am Heart Assoc
Background and Purpose—Nuclear erythroid 2 related factor 2 (Nrf2) is an astrocyte-
enriched transcription factor that has previously been shown to upregulate cellular …

Misleading westerns: common quantification mistakes in western blot densitometry and proposed corrective measures

TAJ Butler, JW Paul, EC Chan, R Smith… - BioMed research …, 2019 - Wiley Online Library
Densitometry data generated for Western blots are commonly used to compare protein
abundance between samples. In the last decade, it has become apparent that assumptions …

Human mesenchymal stem cells/multipotent stromal cells consume accumulated autophagosomes early in differentiation

A Nuschke, M Rodrigues, DB Stolz, CT Chu… - Stem Cell Research & …, 2014 - Springer
Introduction Bone marrow mesenchymal stem cells/multipotent stromal cells (MSCs) are
recruited to sites of injury and subsequently support regeneration through differentiation or …

Immune activated monocyte exosomes alter microRNAs in brain endothelial cells and initiate an inflammatory response through the TLR4/MyD88 pathway

P Dalvi, B Sun, N Tang, L Pulliam - Scientific Reports, 2017 - nature.com
The host immune response is critical for homeostasis; however, when chronic low level
activation of the immune response with or without the driver continues, a cascade of events …

Label-free LC–MS/MS proteomic analysis of cerebrospinal fluid identifies protein/pathway alterations and candidate biomarkers for amyotrophic lateral sclerosis

MA Collins, J An, BL Hood, TP Conrads… - Journal of proteome …, 2015 - ACS Publications
Analysis of the cerebrospinal fluid (CSF) proteome has proven valuable to the study of
neurodegenerative disorders. To identify new protein/pathway alterations and candidate …