Comparative burden of metabolic dysfunction in lean NAFLD vs non-lean NAFLD-a systematic review and meta-analysis

A Tang, CH Ng, PH Phang, KE Chan, YH Chin… - Clinical …, 2023 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD) is traditionally associated with
obesity. However, there is a subtype of NAFLD, namely NAFLD in lean, that occurs without …

[HTML][HTML] The global burden of metabolic disease: Data from 2000 to 2019

NWS Chew, CH Ng, DJH Tan, G Kong, C Lin, YH Chin… - Cell Metabolism, 2023 - cell.com
Global estimates of prevalence, deaths, and disability-adjusted life years (DALYs) from the
Global Burden of Diseases, Injuries, and Risk Factors Study 2019 were examined for …

Shared mechanisms between cardiovascular disease and NAFLD

DQ Huang, M Downes, RM Evans… - Seminars in liver …, 2022 - thieme-connect.com
The burden of nonalcoholic fatty liver disease (NAFLD) is rising globally. Cardiovascular
disease is the leading cause of death in patients with NAFLD. Nearly half of individuals with …

An international multidisciplinary consensus statement on MAFLD and the risk of CVD

XD Zhou, G Targher, CD Byrne, V Somers… - Hepatology …, 2023 - Springer
Background Fatty liver disease in the absence of excessive alcohol consumption is an
increasingly common condition with a global prevalence of~ 25–30% and is also associated …

[HTML][HTML] The effect of diabetes and prediabetes on the prevalence, complications and mortality in nonalcoholic fatty liver disease

CH Ng, KE Chan, YH Chin, RW Zeng… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Methods Data from the National Health and Nutrition Examination Survey 1999–2018 was
used. Hepatic steatosis was defined with United States Fatty Liver Index (US-FLI) and FLI at …

Hypertension is prevalent in non-alcoholic fatty liver disease and increases all-cause and cardiovascular mortality

CH Ng, ZY Wong, NWS Chew, KE Chan… - Frontiers in …, 2022 - frontiersin.org
Background and aims Hypertension (HTN) is a common comorbidity in non-alcoholic fatty
liver disease (NAFLD) affecting up to 40% of individuals. However, the impact of HTN and its …

Risk stratification for sarcopenic obesity in subjects with nonalcoholic fatty liver disease

HS Chun, M Lee, HA Lee, S Lee, S Kim, YJ Jung… - Clinical …, 2023 - Elsevier
Background & Aims The impact of the severity of sarcopenic obesity (SO) in nonalcoholic
fatty liver disease (NAFLD) on the risk of significant liver fibrosis or cardiovascular disease …

[HTML][HTML] Nonalcoholic fatty liver disease and non-liver comorbidities

R Manikat, MH Nguyen - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease characterized by excess
fat accumulation in the liver. It is closely associated with metabolic syndrome, and patients …

Hepatic steatosis and advanced hepatic fibrosis are independent predictors of long‐term mortality in acute myocardial infarction

YH Chin, J Lim, G Kong, CH Ng, R Goh… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To examine the prevalence and prognosis of hepatic steatosis and fibrosis in post‐
acute myocardial infarction (AMI) patients. Methods Patients presenting with AMI to a tertiary …

Nonalcoholic fatty liver disease and cardiovascular diseases: A Mendelian randomization study

H Peng, S Wang, M Wang, Y Ye, E Xue, X Chen… - Metabolism, 2022 - Elsevier
Background Evidence suggests that nonalcoholic fatty liver disease (NAFLD) is associated
with cardiovascular diseases (CVDs). However, the results are inconsistent, and the …