Mammalian genomes express two principal gene categories through RNA polymerase II-
mediated transcription: protein-coding transcription units and non-coding RNA transcription …

Abstract RNA polymerase II (RNA Pol II) speed or elongation rate, ie, the number of
nucleotides synthesized per unit of time, is a major determinant of transcriptome …

Plants have an extraordinary diversity of transcription machineries, including five nuclear
DNA-dependent RNA polymerases. Four of these enzymes are dedicated to the production …

In most organisms, the maturation of nascent RNAs is coupled to transcription. Unlike in
animals, the RNA polymerase II (RNAPII) transcribes microRNA genes (MIRNA s) as long …

Chloroplasts evolved from an ancient cyanobacterial endosymbiont more than 1.5 billion
years ago. During subsequent coevolution with the nuclear genome, the chloroplast …

RNA-mediated chromatin silencing is central to genome regulation in many organisms.
However, how nascent non-coding transcripts regulate chromatin is poorly understood …

Transcriptional memory allows organisms to store information about transcriptional
reprogramming in response to a stimulus. In plants, this often involves the response to an …

MicroRNAs (miRNAs) and natural antisense transcripts (NATs) control many biological
processes and have been broadly applied for genetic manipulation of eukaryotic gene …

Plants monitor many aspects of their fluctuating environments to help align their
development with seasons. Molecular understanding of how noisy temperature cues are …

Various transcript elongation factors (TEFs) including modulators of RNA polymerase II
(RNAPII) activity and histone chaperones tune the efficiency of transcription in the chromatin …