The monoamine hypothesis has significantly improved our understanding of mood disorders
and their treatment by linking monoaminergic abnormalities to the pathophysiology of mood …

Importance The totality of the societal and individual impact of treatment-resistant
depression (TRD) is unknown, as is the potential to prognosticate TRD. The generalizability …

Objective Major depressive disorder (MDD) has a relapse rate that cannot be ignored and
places a tremendous burden on the patient in the prevention and treatment process. Yoga, a …

Background To determine the incidence of Treatment-Resistant Depression (TRD) in Spain
and to estimate its economic burden, using real world data. Methods A retrospective …

Patients with major depressive disorder (MDD) often exhibit an inadequate treatment
response or failure to achieve remission following treatment with antidepressant drugs …

Abstract Treatment-resistant depression (TRD) is a severe form of major depressive disorder
(MDD) with substantial public health impact and poor treatment outcome. Treatment …

Introduction Due to favorable antidepressant (AD) efficacy and tolerability, selective-
serotonin reuptake inhibitors (SSRIs) are consistently recommended as substances of first …

Objective Investigate incidence, risk factors and courses of treatment for treatment-resistant
depression (TRD) in primary and special healthcare. Methods All patients identified from …

Importance Major depressive disorder (MDD) is an important risk factor of suicidal behavior,
but the added burden of suicidal behavior and MDD on the patient and societal level …

Glioma patients carry the burden of having both a progressive neurological disease and
cancer, and may face a variety of symptoms, including depression and anxiety. These …