Depression and anxiety in Parkinson's disease

A Schrag, RN Taddei - International review of neurobiology, 2017 - Elsevier
Depression and anxiety are some of the most common comorbidities arising in patients with
Parkinson's disease. However, their timely recognition and diagnosis are often hindered by …

Gut permeability and microbiota in Parkinson's disease: role of depression, tryptophan catabolites, oxidative and nitrosative stress and melatonergic pathways

G Anderson, M Seo, M Berk… - Current …, 2016 - benthamdirect.com
Background: Increased gut permeability (leaky gut) and alterations in gut microbiota are now
widely accepted as relevant to the etiology, course and treatment of many neuropsychiatric …

Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins

G Anderson, M Maes - Molecular neurobiology, 2014 - Springer
The biological underpinnings to the etiology and course of neurodegeneration in
Parkinson's disease are an area of extensive research that has yet to produce an early …

Non-Motor symptoms in Portuguese Parkinson's Disease patients: correlation and impact on Quality of Life and Activities of Daily Living

P Bugalho, T Lampreia, R Miguel, MD Mendonça… - Scientific reports, 2016 - nature.com
The prevalence of non-motor symptoms (NMS) in Parkinson's Disease (PD) has varied
between studies. Their interrelation isn't totally understood. Also, the relative importance of …

Functional neurological disorder and somatic symptom disorder in Parkinson's disease

M Onofrj, M Russo, C Carrarini, SD Pizzi… - Journal of the …, 2022 - Elsevier
Abstract The occurrence of Functional Neurological Disorder (FND) and Somatic Symptom
Disorder (SSD) in PD was not commonly accepted until recently, despite some evidence that …

Neuronal expression of familial Parkinson's disease A53T α-synuclein causes early motor impairment, reduced anxiety and potential sleep disturbances in mice

SM Rothman, KJ Griffioen, N Vranis… - Journal of …, 2013 - content.iospress.com
Background: Mutations in the human α-synuclein gene lead to early-onset Parkinson's
disease (PD); however, phenotypes of α-synuclein mutant mice vary depending upon the …

Evaluating psychiatric symptoms in Parkinson's Disease by a clinimetric analysis of the Hopkins Symptom Checklist (SCL-90-R)

D Carrozzino, BM Morberg, C Siri, G Pezzoli… - Progress in Neuro …, 2018 - Elsevier
Although psychiatric comorbidity in Parkinson's Disease (PD) has often been studied, the
individual psychiatric symptoms have rarely been evaluated from a clinimetric point of view …

Somatization in Parkinson's disease: a systematic review

D Carrozzino, P Bech, C Patierno, M Onofrj… - Progress in Neuro …, 2017 - Elsevier
The current systematic review study is aimed at critically analyzing from a clinimetric
viewpoint the clinical consequence of somatization in Parkinson's Disease (PD). By focusing …

Impact of mood and behavioral disorders on quality of life in Parkinson's disease

I Rieu, JL Houeto, B Pereira… - Journal of …, 2016 - content.iospress.com
Background: Mood symptoms negatively affect quality of life of Parkinson's disease (PD);
however little is known about the impact of behavioral disorders such as impulse control …

Functional Movement Disorder as a Prodromal Symptom of Parkinson's Disease—Clinical and Pathophysiological Insights

E Matar, M Tinazzi, MJ Edwards… - Movement …, 2024 - Wiley Online Library
Functional movement disorder (FMD) is a common manifestation of functional neurological
disorder. FMD can occur alongside other neurological conditions, but especially in patients …