Mechanisms of HIV-associated lymphocyte apoptosis
Infection with the human immunodeficiency virus (HIV) is associated with a progressive
decrease in CD4 T-cell number and a consequent impairment in host immune defenses …
decrease in CD4 T-cell number and a consequent impairment in host immune defenses …
Idiopathic CD4 Lymphocytopenia: Spectrum of opportunistic infections, malignancies, and autoimmune diseases
DS Ahmad, M Esmadi… - Avicenna journal of …, 2013 - thieme-connect.com
Idiopathic CD4 lymphocytopenia (ICL) was first defined in 1992 by the US Centers for
Disease Control and Prevention (CDC) as the repeated presence of a CD4+ T lymphocyte …
Disease Control and Prevention (CDC) as the repeated presence of a CD4+ T lymphocyte …
Reappraisal of idiopathic CD4 lymphocytopenia at 30 years
A Lisco, AM Ortega-Villa, H Mystakelis… - … England Journal of …, 2023 - Mass Medical Soc
Abstract Background Idiopathic CD4 lymphocytopenia (ICL) is a clinical syndrome that is
defined by CD4 lymphopenia of less than 300 cells per cubic millimeter in the absence of …
defined by CD4 lymphopenia of less than 300 cells per cubic millimeter in the absence of …
Increased TNF-α-induced apoptosis in lymphocytes from aged humans: changes in TNF-α receptor expression and activation of caspases
S Aggarwal, S Gollapudi, S Gupta - The Journal of Immunology, 1999 - journals.aai.org
Aging is characterized by increased T cell lymphopenia, T cell dysfunction, and increased
serum TNF levels. In this study, we have examined the role of TNF-induced apoptosis in T …
serum TNF levels. In this study, we have examined the role of TNF-induced apoptosis in T …
The significance of shed membrane particles during programmed cell death in vitro, and in vivo, in HIV-1 infection.
K Aupeix, B Hugel, T Martin, P Bischoff… - The Journal of …, 1997 - Am Soc Clin Investig
The plasma membrane remodeling, including the early transverse redistribution of
phosphatidylserine, is a general feature occurring in cells in which a death program has …
phosphatidylserine, is a general feature occurring in cells in which a death program has …
Idiopathic CD4+ lymphocytopenia: natural history and prognostic factors
DI Zonios, J Falloon, JE Bennett… - Blood, The Journal …, 2008 - ashpublications.org
Abstract Idiopathic CD4+ lymphocytopenia (ICL) is a rare non–HIV-related syndrome with
unclear natural history and prognosis. This prospective natural history cohort study …
unclear natural history and prognosis. This prospective natural history cohort study …
Primary immunodeficiencies: a rapidly evolving story
The characterization of primary immunodeficiencies (PIDs) in human subjects is crucial for a
better understanding of the biology of the immune response. New achievements in this field …
better understanding of the biology of the immune response. New achievements in this field …
Thrombotic thrombocytopenic purpura and sporadic hemolytic-uremic syndrome plasmas induce apoptosis in restricted lineages of human microvascular endothelial …
D Mitra, EA Jaffe, B Weksler, KA Hajjar… - Blood, The Journal …, 1997 - ashpublications.org
Thrombotic thrombocytopenic purpura (TTP) and sporadic hemolytic-uremic syndrome
(HUS) are thrombotic microangiopathies that occur in the absence of an inflammatory …
(HUS) are thrombotic microangiopathies that occur in the absence of an inflammatory …
Defective expression of p56lck in an infant with severe combined immunodeficiency.
FD Goldman, ZK Ballas, BC Schutte… - The Journal of …, 1998 - Am Soc Clin Investig
Severe combined immune deficiency (SCID) is a heterogeneous disorder characterized by
profound defects in cellular and humoral immunity. We report here an infant with clinical and …
profound defects in cellular and humoral immunity. We report here an infant with clinical and …
Idiopathic CD4 lymphocytopenia
UA Walker, K Warnatz - Current opinion in rheumatology, 2006 - journals.lww.com
The manifestation of opportunistic infections calls for the evaluation of the immune system
for CD4 lymphocytopenia. The differential diagnosis of this condition in adults comprises …
for CD4 lymphocytopenia. The differential diagnosis of this condition in adults comprises …