Drug resistance in epilepsy
E Perucca, P Perucca, HS White, EC Wirrell - The Lancet Neurology, 2023 - thelancet.com
Drug resistance is estimated to affect about a third of individuals with epilepsy, but its
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …
prevalence differs in relation to the epilepsy syndrome, the cause of epilepsy, and other …
Epidemiology of epilepsy and seizures
Epilepsy is a chronic neurological disorder characterised by recurrent unprovoked seizures.
1 It affects an estimated 50 million people worldwide with no socio-demographic boundary …
1 It affects an estimated 50 million people worldwide with no socio-demographic boundary …
Real‐world safety and effectiveness of cenobamate in patients with focal onset seizures: outcomes from an expanded access program
V Villanueva, D Santos‐Carrasco… - Epilepsia …, 2023 - Wiley Online Library
Objective This study investigated early, real‐world outcomes with cenobamate (CNB) in a
large series of patients with highly drug‐resistant epilepsy within a Spanish Expanded …
large series of patients with highly drug‐resistant epilepsy within a Spanish Expanded …
Multicenter, cross‐sectional study of the costs of illness and cost‐driving factors in adult patients with epilepsy
LM Willems, M Hochbaum, K Frey, J Schulz… - …, 2022 - Wiley Online Library
Objective This study was undertaken to quantify epilepsy‐related costs of illness (COI) in
Germany and identify cost‐driving factors. Methods COI were calculated among adults with …
Germany and identify cost‐driving factors. Methods COI were calculated among adults with …
Neuromorphic deep spiking neural networks for seizure detection
The vast majority of studies that process and analyze neural signals are conducted on cloud
computing resources, which is often necessary for the demanding requirements of deep …
computing resources, which is often necessary for the demanding requirements of deep …
Preferences and user experiences of wearable devices in epilepsy: a systematic review and mixed-methods synthesis
Background and Objectives To examine the preferences and user experiences of people
with epilepsy and caregivers regarding automated wearable seizure detection devices …
with epilepsy and caregivers regarding automated wearable seizure detection devices …
Productivity-adjusted life-years: a new metric for quantifying disease burden
For many years, disability-adjusted life-years have been a primary focus of the landmark
Global Burden of Disease studies [1]. Incorporating years of life lost and years of life lived …
Global Burden of Disease studies [1]. Incorporating years of life lost and years of life lived …
Trends in resource utilization and cost of illness in patients with active epilepsy in Germany from 2003 to 2020
LM Willems, M Hochbaum, JP Zöllner, J Schulz… - …, 2022 - Wiley Online Library
Objective This study was undertaken to calculate epilepsy‐related direct, indirect, and total
costs in adult patients with active epilepsy (ongoing unprovoked seizures) in Germany and …
costs in adult patients with active epilepsy (ongoing unprovoked seizures) in Germany and …
Missed, mistaken, stalled: identifying components of delay to diagnosis in epilepsy
N Alessi, P Perucca, AM McIntosh - Epilepsia, 2021 - Wiley Online Library
A substantial proportion of individuals with newly diagnosed epilepsy report prior seizures,
suggesting a missed opportunity for early epilepsy care and management. Consideration of …
suggesting a missed opportunity for early epilepsy care and management. Consideration of …
A multimodal AI system for out-of-distribution generalization of seizure identification
Artificial intelligence (AI) and health sensory data-fusion hold the potential to automate many
laborious and time-consuming processes in hospitals or ambulatory settings, eg home …
laborious and time-consuming processes in hospitals or ambulatory settings, eg home …