The Ras association domain family protein1 isoform A (RASSF1A) is a well-known tumor-
suppressor protein frequently inactivated in various human cancers. Consistent with its …

Simple Summary Epigenetics studies the alteration of gene expression without changing
DNA sequence and very often, epigenetic dysregulation causes cancer. Alternative splicing …

The RASSF1A tumour suppressor is a scaffold protein that is involved in cell signalling.
Increasing evidence shows that this protein sits at the crossroad of a complex signalling …

RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that
influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated …

Endometrial cancer (EC)) is one of the most common malignant tumors of the female genital
system, with an increasing incidence and mortality, worldwide. Although the therapeutic …

Background An increasing number of studies have focused on the early diagnostic value of
the methylation of RASSF1A and SHOX2 in lung cancer. However, the intricate cellular …

Epigenetic changes that regulate chromatin structure have a major impact in genome
stabilization and maintenance of cellular homeostasis, been recently implicated in the …

Malignant pleural mesothelioma is a rare and aggressive neoplasm, which has primarily
been attributed to the exposure to asbestos fibers (83% of cases); yet, despite a ban of using …

Background: Epilepsy (EP) is a very dangerous neurological disease. MiR-181b was
reported to play a regulatory role during the progression of EP. However, the mechanism by …

While significant strides have been made in understanding cancer biology, the
enhancement in patient survival is limited, underscoring the urgency for innovative …