[HTML][HTML] Irregular pore size of degradable bioceramic Voronoi scaffolds prepared by stereolithography: osteogenesis and computational fluid dynamics analysis

J Li, D Guo, J Li, X Wei, Z Sun, B Yang, T Lu… - Materials & Design, 2022 - Elsevier
A Voronoi method is a feasible approach for developing biomimetic trabecular scaffolds.
This study used algorithms based on scaling factors to design Voronoi scaffolds (pore sizes …

[HTML][HTML] Advances in Shear Stress Stimulation of Stem Cells: A Review of the Last Three Decades

Q Lin, Z Yang, H Xu, Y Niu, Q Meng, D Xing - Biomedicines, 2024 - mdpi.com
Stem cells are widely used in scientific research because of their ability to self-renew and
differentiate into a variety of specialized cell types needed for body functions. However, the …

Fluid shear stress regulates osteogenic differentiation via AnnexinA6-mediated autophagy in mc3t3-E1 cells

T Pei, G Su, J Yang, W Gao, X Yang, Y Zhang… - International Journal of …, 2022 - mdpi.com
Fluid shear stress (FSS) facilitates bone remodeling by regulating osteogenic differentiation,
and extracellular matrix maturation and mineralization. However, the underlying molecular …

The potential role of mechanotransduction in the management of pediatric calvarial bone flap repair

H Anderson, DS Hersh, Y Khan - Biotechnology and …, 2024 - Wiley Online Library
Pediatric patients suffering traumatic brain injuries may require a decompressive
craniectomy to accommodate brain swelling by removing a portion of the skull. Once the …

A large‐scale production of mesenchymal stem cells and their exosomes for an efficient treatment against lung inflammation

J Zhang, R Lin, Y Li, J Wang, H Ding… - Biotechnology …, 2024 - Wiley Online Library
Mesenchymal stem cells (MSCs) and their produced exosomes have demonstrated inherent
capabilities of inflammation‐guided targeting and inflammatory modulation, inspiring their …

METTL3-mediated m6A modification increases Hspa1a stability to inhibit osteoblast aging

Y Wang, Y Chen, H Xiao, Z Liu, X Liu, Z Feng… - Cell Death …, 2024 - nature.com
Senile osteoporosis is mainly caused by osteoblasts attenuation, which results in reduced
bone mass and disrupted bone remodeling. Numerous studies have focused on the …

Identification of osteoblastic autophagy-related genes for predicting diagnostic markers in osteoarthritis

R Cai, Q Jiang, D Chen, Q Feng, X Liang, Z Ouyang… - iScience, 2024 - cell.com
The development of osteoarthritis (OA) involves subchondral bone lesions, but the role of
osteoblastic autophagy-related genes (ARGs) in osteoarthritis is unclear. Through integrated …

Universal Biomaterial-on-Chip: a versatile platform for evaluating cellular responses on diverse biomaterial substrates

AR Atif, M Aramesh, SS Carter, M Tenje… - Journal of Materials …, 2024 - Springer
Microfluidics has emerged as a promising approach for assessing cellular behavior in vitro,
providing more physiologically relevant cell culture environments with dynamic flow and …

[PDF][PDF] Effect of Wall Shear Stress on Myoblast Orientation Distribution

H YONEZAWA, S HASHIMOTO, R ONO - Proc. 14th International Multi …, 2023 - iiis.org
The effect of wall shear stress on the orientation of cells was examined in vitro. Couette-type
shear flow device was made between the lower fixed culture plate and the upper rotating …