Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

[HTML][HTML] Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J Xiang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

[HTML][HTML] Multifunctional biomolecule nanostructures for cancer therapy

J Wang, Y Li, G Nie - Nature Reviews Materials, 2021 - nature.com
Biomolecule-based nanostructures are inherently multifunctional and harbour diverse
biological activities, which can be explored for cancer nanomedicine. The supramolecular …

Near infrared photothermal conversion materials: Mechanism, preparation, and photothermal cancer therapy applications

J Li, W Zhang, W Ji, J Wang, N Wang, W Wu… - Journal of Materials …, 2021 - pubs.rsc.org
Photothermal therapy (PTT) has been widely applied in cancer therapy as a result of its non-
invasive, localized treatment and good therapeutic effect. In general, the final therapeutic …

[HTML][HTML] Depletion of tumor associated macrophages enhances local and systemic platelet-mediated anti-PD-1 delivery for post-surgery tumor recurrence treatment

Z Li, Y Ding, J Liu, J Wang, F Mo, Y Wang… - Nature …, 2022 - nature.com
Immunosuppressive cells residing in the tumor microenvironment, especially tumor
associated macrophages (TAMs), hinder the infiltration and activation of T cells, limiting the …

The use of alternative strategies for enhanced nanoparticle delivery to solid tumors

M Izci, C Maksoudian, BB Manshian… - Chemical …, 2021 - ACS Publications
Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Stealth nanoparticles in oncology: Facing the PEG dilemma

S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …

Immune cell Membrane‐Coated biomimetic nanoparticles for targeted cancer therapy

F Oroojalian, M Beygi, B Baradaran, A Mokhtarzadeh… - Small, 2021 - Wiley Online Library
Nanotechnology has provided great opportunities for managing neoplastic conditions at
various levels, from preventive and diagnostic to therapeutic fields. However, when it comes …

[HTML][HTML] Surface-bound reactive oxygen species generating nanozymes for selective antibacterial action

F Gao, T Shao, Y Yu, Y Xiong, L Yang - Nature communications, 2021 - nature.com
Acting by producing reactive oxygen species (ROS) in situ, nanozymes are promising as
antimicrobials. ROS'intrinsic inability to distinguish bacteria from mammalian cells, however …