Next-generation sequencing for confronting virus pandemics
Virus pandemics have happened, are happening and will happen again. In recent decades,
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
the rate of zoonotic viral spillover into humans has accelerated, mirroring the expansion of …
Deep-sequencing reveals broad subtype-specific HCV resistance mutations associated with treatment failure
A percentage of hepatitis C virus (HCV)-infected patients fail direct acting antiviral (DAA)-
based treatment regimens, often because of drug resistance-associated substitutions (RAS) …
based treatment regimens, often because of drug resistance-associated substitutions (RAS) …
Safety and efficacy of combined sofosbuvir/daclatasvir treatment of children and adolescents with chronic hepatitis C genotype 4
TY Abdel Ghaffar, S El Naghi… - Journal of viral …, 2019 - Wiley Online Library
Direct‐acting antivirals have become available for treating chronic HCV (hepatitis C virus)
infection in adults and, recently, in children at least 12 years old. Our aim was to investigate …
infection in adults and, recently, in children at least 12 years old. Our aim was to investigate …
Pipeline for specific subtype amplification and drug resistance detection in hepatitis C virus
ME Soria, J Gregori, Q Chen, D García-Cehic… - BMC Infectious …, 2018 - Springer
Background Despite the high sustained virological response rates achieved with current
directly-acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 5–10% of …
directly-acting antiviral agents (DAAs) against hepatitis C virus (HCV), around 5–10% of …
Full-genome next-generation sequencing of hepatitis C virus to assess the accuracy of genotyping by the commercial assay LiPA and the prevalence of resistance …
KT Christensen, F Pierard, K Beuselinck… - Journal of Clinical …, 2022 - Elsevier
Background Although most currently used regimens for Hepatitis C virus (HCV) infections
can be initiated without prior knowledge of genotype and subtype, genotyping is still useful …
can be initiated without prior knowledge of genotype and subtype, genotyping is still useful …
Evaluation of 8‐week glecaprevir/pibrentasvir treatment in direct‐acting antiviral‐naïve noncirrhotic HCV genotype 1 and 2infected patients in a real‐world setting in …
H Ikeda, T Watanabe, M Atsukawa… - Journal of Viral …, 2019 - Wiley Online Library
Based on high efficacy and safety demonstrated in clinical trials, treatment with glecaprevir/
pibrentasvir (G/P) for 8 weeks is recommended for hepatitis C virus (HCV)–infected patients …
pibrentasvir (G/P) for 8 weeks is recommended for hepatitis C virus (HCV)–infected patients …
A novel standardized deep sequencing-based assay for hepatitis C virus genotype determination
C Rodriguez, A Soulier, V Demontant, L Poiteau… - Scientific Reports, 2018 - nature.com
Hepatitis C virus (HCV) genotype and subtype (1a/1b) identification is needed to tailor anti-
HCV therapy. Currently available methods accurately identify the genotype and differentiate …
HCV therapy. Currently available methods accurately identify the genotype and differentiate …
The EIMB hydrogel microarray technology: thirty years later
DA Gryadunov, BL Shaskolskiy… - Acta Naturae …, 2018 - cyberleninka.ru
Biological microarrays (biochips) are analytical tools that can be used to implement complex
integrative genomic and proteomic approaches to the solution of problems of personalized …
integrative genomic and proteomic approaches to the solution of problems of personalized …
Reliable resolution of ambiguous hepatitis C virus genotype 1 results with the Abbott HCV Genotype Plus RUO assay
V Saludes, A Antuori, B Reinhardt, I Viciana… - Scientific reports, 2019 - nature.com
Accurate subtyping of hepatitis C virus genotype 1 (HCV-1) remains clinically and
epidemiologically relevant. The Abbott HCV Genotype Plus RUO (GT Plus) assay, targeting …
epidemiologically relevant. The Abbott HCV Genotype Plus RUO (GT Plus) assay, targeting …
Whole-genome characterization and resistance-associated substitutions in a new HCV genotype 1 subtype
G Von Massow, D Garcia-Cehic, J Gregori… - Infection and drug …, 2019 - Taylor & Francis
Hepatitis C virus (HCV) is a highly variable infectious agent, classified into 8 genotypes and
86 subtypes. Our laboratory has implemented an in-house developed high-resolution HCV …
86 subtypes. Our laboratory has implemented an in-house developed high-resolution HCV …