Why not try harder? Computational approach to motivation deficits in neuro-psychiatric diseases
Motivation deficits, such as apathy, are pervasive in both neurological and psychiatric
diseases. Even when they are not the core symptom, they reduce quality of life, compromise …
diseases. Even when they are not the core symptom, they reduce quality of life, compromise …
Clinical predictors of therapeutic response to antipsychotics in schizophrenia
M Carbon, CU Correll - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
The search for clinical outcome predictors for schizophrenia is as old as the field of
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …
EPA guidance on assessment of negative symptoms in schizophrenia
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …
brought about by the increased awareness that they interfere severely with real-life …
The current conceptualization of negative symptoms in schizophrenia
SR Marder, S Galderisi - World Psychiatry, 2017 - Wiley Online Library
Negative symptoms have long been conceptualized as a core aspect of schizophrenia. They
play a key role in the functional outcome of the disorder, and their management represents a …
play a key role in the functional outcome of the disorder, and their management represents a …
Second‐generation antipsychotic effect on cognition in patients with schizophrenia—a meta‐analysis of randomized clinical trials
RE Nielsen, S Levander… - Acta Psychiatrica …, 2015 - Wiley Online Library
Objective To investigate the effect of second‐generation antipsychotics on cognitive function
in patients diagnosed with schizophrenia or schizoaffective disorder. Method Multiple …
in patients diagnosed with schizophrenia or schizoaffective disorder. Method Multiple …
Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia
M Carbon, CU Correll - CNS spectrums, 2014 - cambridge.org
Since currently available antipsychotic medications predominantly treat hallucinations,
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …
Pathophysiology of negative symptom dimensions of schizophrenia–current developments and implications for treatment
Negative symptoms of schizophrenia comprise a group of severe symptoms contributing to
high disease burden and poor long-term prognosis. Conceptual work has shown that these …
high disease burden and poor long-term prognosis. Conceptual work has shown that these …
Motivational deficits in early schizophrenia: prevalent, persistent, and key determinants of functional outcome
G Fervaha, G Foussias, O Agid, G Remington - Schizophrenia research, 2015 - Elsevier
Negative symptoms, in particular motivational deficits, are reported as impediments to
functional recovery in patients with schizophrenia. This study examined the prevalence of …
functional recovery in patients with schizophrenia. This study examined the prevalence of …
The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors
W Fleischhacker, S Galderisi, I Laszlovszky… - European …, 2019 - cambridge.org
Background: Negative symptoms in schizophrenia are heterogeneous and
multidimensional; effective treatments are lacking. Cariprazine, a dopamine D3-preferring …
multidimensional; effective treatments are lacking. Cariprazine, a dopamine D3-preferring …
[PDF][PDF] Standards für die Behandlung im Maßregelvollzug nach §§ 63 und 64 StGB.
Die Behandlung in den Kliniken für Forensische Psychiatrie und Psychotherapie und den
forensisch psychiatrischen Ambulanzen ist Teil des Versorgungsangebots für psychisch …
forensisch psychiatrischen Ambulanzen ist Teil des Versorgungsangebots für psychisch …