NOACs versus warfarin for stroke prevention in patients with AF: a systematic review and meta-analysis

T Hicks, F Stewart, A Eisinga - Open heart, 2016 - openheart.bmj.com
Background Warfarin has been the anticoagulant of choice for the prevention of ischaemic
stroke in patients with atrial fibrillation (AF). Novel oral anticoagulants (NOACs) are …

Anti-arrhythmic strategies for atrial fibrillation: The role of computational modeling in discovery, development, and optimization

E Grandi, MM Maleckar - Pharmacology & therapeutics, 2016 - Elsevier
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with increased risk
of cerebrovascular stroke, and with several other pathologies, including heart failure …

Computational assessment of the relation between embolism source and embolus distribution to the circle of Willis for improved understanding of stroke etiology

D Mukherjee, ND Jani… - Journal of …, 2016 - asmedigitalcollection.asme.org
Stroke caused by an embolism accounts for about a third of all stroke cases. Understanding
the source and cause of the embolism is critical for diagnosis and long-term treatment of …

Effects of ageing on aortic circulation during atrial fibrillation; a numerical study on different aortic morphologies

A Deyranlou, CA Miller, A Revell, A Keshmiri - Annals of Biomedical …, 2021 - Springer
Atrial fibrillation (AF) can alter intra-cardiac flow and cardiac output that subsequently affects
aortic flow circulation. These changes may become more significant where they occur …

Dynamic modeling for a flexible spacecraft with solar arrays composed of honeycomb panels and its proportional–derivative control with input shaper

L Liu, D Cao - Journal of dynamic systems …, 2016 - asmedigitalcollection.asme.org
A high-precision dynamic model of a flexible spacecraft installed with solar arrays, which are
composed of honeycomb panels, is established based on the nonconstrained modes of …

A resolved two-way coupled CFD/6-DOF approach for predicting embolus transport and the embolus-trapping efficiency of IVC filters

KI Aycock, RL Campbell, KB Manning… - … and Modeling in …, 2017 - Springer
Inferior vena cava (IVC) filters are medical devices designed to provide a mechanical barrier
to the passage of emboli from the deep veins of the legs to the heart and lungs. Despite …

Blood–brain barrier disruption in atrial fibrillation: a potential contributor to the increased risk of dementia and worsening of stroke outcomes?

R Aryal, A Patabendige - Open Biology, 2021 - royalsocietypublishing.org
Atrial fibrillation (AF) has become one of the most significant health problems worldwide,
warranting urgent answers to currently pending questions on the effects of AF on brain …

The relation between aortic arch branching types and the laterality of cardio-embolic stroke

N Elsaid, G Bigliardi, ML Dell'Acqua, L Vandelli… - Journal of Stroke and …, 2020 - Elsevier
Background and purpose The trajectory of cardiogenic emboli could be affected by
anatomical and flow characteristics of the aortic arch. We aimed to study the relation …

Embolus analog trajectory paths under physiological flowrates through patient-specific aortic arch models

F Malone, E McCarthy… - Journal of …, 2019 - asmedigitalcollection.asme.org
Atrial fibrillation (AF) is the most common irregular heartbeat among the world's population
and is a major contributor to cardiogenic embolisms and acute ischemic stroke (AIS) …

Investigation of the hemodynamics influencing emboli trajectories through a patient-specific aortic arch model

F Malone, E McCarthy, P Delassus, JH Buhk, J Fiehler… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—Cardiogenic emboli account for 15% to 20% of acute ischemic
stroke cases worldwide. However, the chance of such emboli, of varying sizes, causing a …