It is more than 50 years since the Epstein–Barr virus (EBV), the first human tumour virus, was
discovered. EBV has subsequently been found to be associated with a diverse range of …

Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

Burkitt's lymphoma is a highly aggressive B-cell non-Hodgkin lymphoma and is the fastest
growing human tumour. The disease is associated with Epstein-Barr virus and was one of …

Epstein–Barr virus (EBV) was discovered 40 years ago from examining electron
micrographs of cells cultured from Burkitt's lymphoma, a childhood tumour that is common in …

EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

Epstein–Barr virus (EBV) is the first identified human oncogenic virus that can establish
asymptomatic life-long persistence. It is associated with a large spectrum of diseases …

The gene encoding latent-infection membrane protein 1 (LMP1) was specifically mutated in
Epstein-Barr virus (EBV) recombinants by inserting a nonsense linker after codon 9 or codon …

The cytoplasmic C-terminus of Epstein-Barr virus (EBV) latent infection membrane protein 1
(LMP1) is essential for B lymphocyte growth transformation and is now shown to interact with …

Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical
syndromes in its natural host, the chicken. MDV has long been of interest as a model …

With current techniques, genetic alterations of herpesviruses are difficult to perform, mostly
because of the large size of their genomes. To solve this problem, we have designed a …