Thermo-responsive polymers: Applications of smart materials in drug delivery and tissue engineering

M Sponchioni, UC Palmiero, D Moscatelli - Materials Science and …, 2019 - Elsevier
Synthetic polymers are attracting great attention in the last decades for their use in the
biomedical field as nanovectors for controlled drug delivery, hydrogels and scaffolds …

Stem cell-derived cell sheet transplantation for heart tissue repair in myocardial infarction

R Guo, M Morimatsu, T Feng, F Lan, D Chang… - Stem Cell Research & …, 2020 - Springer
Stem cell-derived sheet engineering has been developed as the next-generation treatment
for myocardial infarction (MI) and offers attractive advantages in comparison with direct stem …

Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart

HC Ott, TS Matthiesen, SK Goh, LD Black, SM Kren… - Nature medicine, 2008 - nature.com
About 3,000 individuals in the United States are awaiting a donor heart; worldwide, 22
million individuals are living with heart failure. A bioartificial heart is a theoretical alternative …

Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro

Y Haraguchi, T Shimizu, T Sasagawa, H Sekine… - Nature protocols, 2012 - nature.com
The fabrication of 3D tissues retaining the original functions of tissues/organs in vitro is
crucial for optimal tissue engineering and regenerative medicine. The fabrication of 3D …

Reconstruction of functional tissues with cell sheet engineering

J Yang, M Yamato, T Shimizu, H Sekine, K Ohashi… - Biomaterials, 2007 - Elsevier
The field of tissue engineering has yielded several successes in early clinical trials of
regenerative medicine using living cells seeded into biodegradable scaffolds. In contrast to …

Endothelial cell coculture within tissue-engineered cardiomyocyte sheets enhances neovascularization and improves cardiac function of ischemic hearts

H Sekine, T Shimizu, K Hobo, S Sekiya, J Yang… - Circulation, 2008 - Am Heart Assoc
Background—Regenerative therapies, including myocardial tissue engineering, have been
pursued as a new possibility to repair the damaged myocardium, and previously the …

Myocardial tissue engineering: a review

H Jawad, NN Ali, AR Lyon, QZ Chen… - Journal of tissue …, 2007 - Wiley Online Library
Myocardial tissue engineering, a concept that intends to overcome the obstacles to
prolonging patients' life after myocardial infarction, is continuously improving. It comprises a …

Thermally-triggered fabrication of cell sheets for tissue engineering and regenerative medicine

H Takahashi, T Okano - Advanced drug delivery reviews, 2019 - Elsevier
Cell transplantation is a promising approach for promoting tissue regeneration in the
treatment of damaged tissues or organs. Although cells have conventionally been delivered …

Temperature-responsive cell culture surfaces for regenerative medicine with cell sheet engineering

M Yamato, Y Akiyama, J Kobayashi, J Yang… - Progress in Polymer …, 2007 - Elsevier
We have developed a novel strategy for regenerative medicine to recover tissue functions by
using temperature-responsive cell culture surfaces. To overcome the limits of conventional …

Cell sheet engineering for heart tissue repair

S Masuda, T Shimizu, M Yamato, T Okano - Advanced drug delivery …, 2008 - Elsevier
Recently, myocardial tissue engineering has emerged as one of the most promising
therapies for patients suffering from severe heart failure. Nevertheless, conventional …