NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function

TR Alderson, LE Kay - Cell, 2021 - cell.com
Biomolecules are in constant motion. To understand how they function, and why
malfunctions can cause disease, it is necessary to describe their three-dimensional …

The multifaceted roles of proline in cell behavior

EJ Patriarca, F Cermola, C D'Aniello, A Fico… - Frontiers in cell and …, 2021 - frontiersin.org
Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino
acid is:(i) A main precursor of extracellular collagens (the most abundant human proteins) …

NMR illuminates intrinsic disorder

HJ Dyson, PE Wright - Current opinion in structural biology, 2021 - Elsevier
Nuclear magnetic resonance (NMR) has long been instrumental in the characterization of
intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs). This …

Heterogeneity in protein folding and unfolding reactions

S Bhatia, JB Udgaonkar - Chemical Reviews, 2022 - ACS Publications
Proteins have dynamic structures that undergo chain motions on time scales spanning from
picoseconds to seconds. Resolving the resultant conformational heterogeneity is essential …

ODiNPred: comprehensive prediction of protein order and disorder

R Dass, FAA Mulder, JT Nielsen - Scientific Reports, 2020 - nature.com
Structural disorder is widespread in eukaryotic proteins and is vital for their function in
diverse biological processes. It is therefore highly desirable to be able to predict the degree …

Experimental NOE, chemical shift, and proline isomerization data provide detailed insights into amelotin oligomerization

SC Chiliveri, Y Shen, JL Baber, J Ying… - Journal of the …, 2023 - ACS Publications
Amelotin is an intrinsically disordered protein (IDP) rich in Pro residues and is involved in
hydroxyapatite mineralization. It rapidly oligomerizes under physiological conditions of pH …

13C Direct Detected NMR for Challenging Systems

IC Felli, R Pierattelli - Chemical Reviews, 2022 - ACS Publications
Thanks to recent improvements in NMR spectrometer hardware and pulse sequence design,
modern 13C NMR has become a useful tool for biomolecular applications. The complete …

[HTML][HTML] Phytoremediation potential of Bermuda grass (Cynodon dactylon (L.) pers.) in soils co-contaminated with polycyclic aromatic hydrocarbons and cadmium

X Song, C Li, W Chen - Ecotoxicology and Environmental Safety, 2022 - Elsevier
Soils co-contaminated with polycyclic aromatic hydrocarbons (PAHs) and cadmium (Cd)
have serious environmental impacts and are highly toxic to humans and ecosystems …

Environmental sustainability and resilience in a polluted ecosystem via phytoremediation of heavy metals and plant physiological adaptations

Z Ahmad, SM Khan, SE Page, H Balzter, A Ullah… - Journal of Cleaner …, 2023 - Elsevier
Natural Ecosystems are being degraded significantly due to increasing industrial pollution.
Marble pollution is one of them. It was hypothesized that such a polluted ecosystem host …

Politics of the natural vegetation to balance the hazardous level of elements in marble polluted ecosystem through phytoremediation and physiological responses

Z Ahmad, SM Khan, S Page - Journal of hazardous materials, 2021 - Elsevier
The current paper evaluates the phytoremediation ability and physiological responses of
selected resistant plant species to the hazardous levels of elements in the marble waste …