Current developments of coumarin-based anti-cancer agents in medicinal chemistry

S Emami, S Dadashpour - European Journal of Medicinal Chemistry, 2015 - Elsevier
Cancer is one of the leading health hazards and the prominent cause of death in the world.
A number of anticancer agents are currently in clinical practice and used for treatment of …

Coumarins as anticancer agents: A review on synthetic strategies, mechanism of action and SAR studies

A Thakur, R Singla, V Jaitak - European journal of medicinal chemistry, 2015 - Elsevier
Coumarins are fused benzene and pyrone ring systems which prompt biological
investigation to assess their potential therapeutic significance. It possesses immeasurable …

Green synthesis and evaluation of antiangiogenic, photocatalytic, and electrochemical activities of BiVO4 nanoparticles

C Mallikarjunaswamy, S Pramila, G Nagaraju… - Journal of Materials …, 2021 - Springer
Nanocrystalline bismuth vanadate has been steadily gaining attention in recent years due to
its potential energy conversion and eco-friendly nature. Herein, we report the green …

[PDF][PDF] Pharmacologically potentials of different substituted coumarin derivatives

M Asif - Chem. Int, 2015 - academia.edu
Coumarins are well recognized naturally occurring compounds which isolated and present
in large number of compounds in the plant kingdom. Mostly occur in higher plants, richest …

[HTML][HTML] Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma

T Prashanth, BRV Avin, P Thirusangu… - Biomedicine & …, 2019 - Elsevier
The synthesis and antiproliferative effect of a series of quinoline and thiazole containing
coumarin analogs 12a-d and 13a-f respectively, on mice leukemic cells was performed. The …

Coumarin sulfonamide derivatives: An emerging class of therapeutic agents

A Irfan, L Rubab, MU Rehman, R Anjum… - Heterocyclic …, 2020 - degruyter.com
Coumarin sulfonamide is a heterocyclic pharmacophore and an important structural motif
which is a core and integral part of different therapeutic scaffolds and analogues. Coumarin …

[HTML][HTML] The anti-proliferative activity of novel 4H-benzo [h] chromenes, 7H-benzo [h]-chromeno [2, 3-d] pyrimidines and the structure–activity relationships of the 2-, 3 …

AM El-Agrody, AH Halawa, AM Fouda… - Journal of Saudi …, 2017 - Elsevier
In the present study, novel derivatives of 4H-benzo [h] chromene and 7H-benzo [h]
chromeno [2, 3-d] pyrimidine were prepared and evaluated for their anti-proliferative activity …

Fe3O4‐supported sulfonated graphene oxide as a green and magnetically separable nanocatalyst for synthesis of 2-amino-3-cyano-4H-chromene derivatives and …

S Sharma, M Meena, H Sharma, DK Yadav… - Synthetic …, 2022 - Taylor & Francis
Under ultrasound irradiation, 17 examples of 2-Amino-3-cyano-4H-chromene derivatives
were prepared via one-pot three components domino Knoevenagel–Michael condensation …

3, 5-Disubstituted isoxazole derivatives: Potential inhibitors of inflammation and cancer

KS Rakesh, S Jagadish, KS Balaji, F Zameer… - Inflammation, 2016 - Springer
The products of arachidonic acid metabolism by lipoxygenase (LOX) and cyclooxygenase
(COX) significantly contribute to inflammation and carcinogenesis. Particularly …

Characterization of novel heterocyclic compounds based on 4-aryl-4H-chromene scaffold as anticancer agents: Design, synthesis, antiprofilerative activity against …

EKA Abdelall, HAH Elshemy, MB Labib… - Bioorganic …, 2022 - Elsevier
In this study, three novel sets of 4-aryl-4H-chromene derivatives 4a–c, 6a–d and 7a–c were
synthesized and evaluated for anticancer activity. Characterization of new compounds was …