Pathophysiological roles of chronic low‐grade inflammation mediators in polycystic ovary syndrome

M Rostamtabar, S Esmaeilzadeh… - Journal of cellular …, 2021 - Wiley Online Library
Polycystic ovary syndrome (PCOS) is the most common hormonal imbalance disease in
reproductive‐aged women. Its basic characteristics are ovulatory dysfunction and ovarian …

Toll-like receptors in sepsis-associated cytokine storm and their endogenous negative regulators as future immunomodulatory targets

V Kumar - International immunopharmacology, 2020 - Elsevier
Cytokine storm generates during various systemic acute infections, including sepsis and
current pandemic called COVID-19 (severe) causing devastating inflammatory conditions …

Tumor-initiating cells establish an IL-33–TGF-β niche signaling loop to promote cancer progression

S Taniguchi, A Elhance, A Van Duzer, S Kumar… - Science, 2020 - science.org
INTRODUCTION A small subset of tumor cells with long-term tumorigenic capacity, known
as tumor-initiating cells (TICs), play a pivotal role in cancer development and therapy …

Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association

SL Chow, AS Maisel, I Anand, B Bozkurt, RA De Boer… - Circulation, 2017 - Am Heart Assoc
Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …

Neutrophils orchestrate post-myocardial infarction healing by polarizing macrophages towards a reparative phenotype

M Horckmans, L Ring, J Duchene… - European heart …, 2017 - academic.oup.com
Aims Acute myocardial infarction (MI) is the leading cause of mortality worldwide. Anti-
inflammatory strategies to reduce neutrophil-driven acute post-MI injury have been shown to …

Congestion in heart failure: a circulating biomarker‐based perspective. A review from the Biomarkers Working Group of the Heart Failure Association, European …

J Núñez, R de la Espriella, P Rossignol… - European Journal of …, 2022 - Wiley Online Library
Congestion is a cardinal sign of heart failure (HF). In the past, it was seen as a
homogeneous epiphenomenon that identified patients with advanced HF. However, current …

[HTML][HTML] The central role of IL-33/IL-1RL1 pathway in asthma: from pathogenesis to intervention

AKS Jayalatha, L Hesse, ME Ketelaar… - Pharmacology & …, 2021 - Elsevier
Abstract Interleukin-33 (IL-33), a member of the IL-1 family, and its cognate receptor,
Interleukin-1 receptor like-1 (IL-1RL1 or ST2), are susceptibility genes for childhood asthma …

Imaging, biomarker, and clinical predictors of cardiac remodeling in heart failure with reduced ejection fraction

A Aimo, HK Gaggin, A Barison, M Emdin, JL Januzzi - JACC: Heart Failure, 2019 - jacc.org
In response to injury, hemodynamic changes, or neurohormonal activation, the heart
undergoes a series of structural and functional changes that have been termed cardiac …

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells

A Vasanthakumar, K Moro, A Xin, Y Liao, R Gloury… - Nature …, 2015 - nature.com
Abstract Foxp3+ regulatory T (Treg) cells in visceral adipose tissue (VAT-Treg cells) are
functionally specialized tissue-resident cells that prevent obesity-associated inflammation …

New fronts emerge in the influenza cytokine storm

XJ Guo, PG Thomas - Seminars in immunopathology, 2017 - Springer
Influenza virus is a significant pathogen in humans and animals with the ability to cause
extensive morbidity and mortality. Exuberant immune responses induced following infection …