Promising biomarkers of radiation-induced lung injury: a review

X Liu, C Shao, J Fu - Biomedicines, 2021 - mdpi.com
Radiation-induced lung injury (RILI) is one of the main dose-limiting side effects in patients
with thoracic cancer during radiotherapy. No reliable predictors or accurate risk models are …

Targeting mitochondrial metabolism to reverse radioresistance: an alternative to glucose metabolism

C Bian, Z Zheng, J Su, H Wang, S Chang, Y Xin… - Antioxidants, 2022 - mdpi.com
Radiotherapy failure and poor tumor prognosis are primarily attributed to radioresistance.
Improving the curative effect of radiotherapy and delaying cancer progression have become …

Radiation-assisted reduction of graphene oxide by aloe vera and ginger and their antioxidant and anti-inflammatory roles against male mice liver injury induced by …

MM Atta, ME Habieb, MAEH Mohamed… - New Journal of …, 2022 - pubs.rsc.org
A novel method for graphene oxide (GO) reduction using γ-rays in the presence of natural
antioxidants is revealed to be a promising eco-friendly and safe approach for producing …

Gut microbiota-derived PGF2α fights against radiation-induced lung toxicity through the MAPK/NF-κB pathway

ZY Chen, HW Xiao, JL Dong, Y Li, B Wang, SJ Fan… - Antioxidants, 2021 - mdpi.com
Radiation pneumonia is a common and intractable side effect associated with radiotherapy
for chest cancer and involves oxidative stress damage and inflammation, prematurely …

Microbiome in radiotherapy: an emerging approach to enhance treatment efficacy and reduce tissue injury

L Lu, F Li, Y Gao, S Kang, J Li, J Guo - Molecular Medicine, 2024 - Springer
Radiotherapy is a widely used cancer treatment that utilizes powerful radiation to destroy
cancer cells and shrink tumors. While radiation can be beneficial, it can also harm the …

Serum RNA biomarkers for predicting survival in non-human primates following thoracic radiation

JM May, U Shankavaram, MA Bylicky, S Chopra… - Scientific Reports, 2022 - nature.com
In a mass radiation exposure, the healthcare system may rely on differential expression of
miRNA to determine exposure and effectively allocate resources. To this end, miRNome …

New insights on old biomarkers involved in tumor microenvironment changes and their diagnostic relevance in non-small cell lung carcinoma

K Wadowska, P Błasiak, A Rzechonek, I Bil-Lula… - Biomolecules, 2021 - mdpi.com
Background: Lung cancer is a multifactorial disease with a heterogeneous tumor group that
hampers diagnostic and therapeutic approaches, as well as understanding of the processes …

Associations between patient-reported late effects and systemic cytokines in long-term survivors of head and neck cancer treated with radiotherapy

TTM Huynh, HCD Aass, RS Falk, GL Astrup… - Journal of Cancer …, 2023 - Springer
Purpose Head and neck cancer (HNC) treatment may lead to late effects and impaired
health-related quality of life of survivors. Knowledge on long-term late effects after …

IDO1 activity predicts lung toxicity in patients with unresectable stage III NSCLC and chemoradiotherapy

L Wu, Y Gao, D Wang, Y Chen, M Qian, X Xu… - Journal of …, 2023 - Wiley Online Library
Objectives. Indoleamine 2, 3‐dioxygenase 1 (IDO1) acts as the key rate‐limiting enzyme that
converts tryptophan (Trp) to kynurenine (Kyn). Its activity was primarily induced by interferon …

Development of a Radiation-induced Pulmonary Fibrosis Partial Body Irradiation Model in C57BL/6 Mice

VP Kumar, S Jaiswal, K Wuddie… - Radiation …, 2024 - meridian.allenpress.com
With the current volatile geopolitical climate, the threat of nuclear assault is high. Exposure
to ionizing radiation from either nuclear incidents or radiological accidents often lead to …