Anthelmintic resistance in ruminants: Challenges and solutions

J Charlier, DJ Bartley, S Sotiraki… - Advances in …, 2022 - Elsevier
Anthelmintic resistance (AR) is a growing concern for effective parasite control in farmed
ruminants globally. Combatting AR will require intensified and integrated research efforts in …

Anthelmintic resistance and its mechanism: a review

W Fissiha, MZ Kinde - Infection and Drug Resistance, 2021 - Taylor & Francis
Helminths are a various types of parasites causing a major health problem for animals in
different parts of the globe. Control of helminthiasis has largely relied on the use of …

Anthelmintic resistance in Haemonchus contortus: history, mechanisms and diagnosis

AC Kotze, RK Prichard - Advances in parasitology, 2016 - Elsevier
Haemonchus contortus has shown a great ability to develop resistance to anthelmintic
drugs. In many instances, resistance has appeared less than 10 years after the introduction …

[HTML][HTML] Impact of gastrointestinal parasitic nematodes of sheep, and the role of advanced molecular tools for exploring epidemiology and drug resistance-an …

F Roeber, AR Jex, RB Gasser - Parasites & vectors, 2013 - Springer
Parasitic nematodes (roundworms) of small ruminants and other livestock have major
economic impacts worldwide. Despite the impact of the diseases caused by these …

[HTML][HTML] Multiple drug resistance in the canine hookworm Ancylostoma caninum: an emerging threat?

PD Jimenez Castro, SB Howell, JJ Schaefer… - Parasites & vectors, 2019 - Springer
Abstract Background The canine hookworm, Ancylostoma caninum is the most prevalent
and important intestinal nematode parasite of dogs in the USA. Hookworms are typically well …

Phenotyping and genotyping of Haemonchus contortus isolates reveals a new putative candidate mutation for benzimidazole resistance in nematodes

M Ghisi, R Kaminsky, P Mäser - Veterinary parasitology, 2007 - Elsevier
In order to monitor and eventually control the spread of drug-resistant Haemonchus
contortus, knowledge of the molecular mechanisms underlying resistance is essential. Here …

Deep amplicon sequencing as a powerful new tool to screen for sequence polymorphisms associated with anthelmintic resistance in parasitic nematode populations

RW Avramenko, EM Redman, L Melville… - International Journal for …, 2019 - Elsevier
Parasitic gastrointestinal nematodes contribute to significant human morbidity and cause
billions of dollars per year in lost agricultural production. Control is dependent on the use of …

Benzimidazole resistance in helminths: From problem to diagnosis

LFV Furtado, ACP de Paiva Bello, ÉML Rabelo - Acta tropica, 2016 - Elsevier
Helminth parasites cause significant morbidity and mortality in endemic countries. Given the
severity of symptoms that helminths may elicit in the host, intervention with prophylactic and …

Molecular detection of benzimidazole resistance in Haemonchus contortus using real-time PCR and pyrosequencing

G von Samson-Himmelstjerna, TK Walsh, AA Donnan… - Parasitology, 2009 - cambridge.org
Benzimidazoles (BZ) are widely used to treat parasitic nematode infections of humans and
animals, but resistance is widespread in veterinary parasites. Several polymorphisms in β …

Genetic analysis of a relationship between macrocyclic lactone and benzimidazole anthelmintic selection on Haemonchus contortus

M de Lourdes Mottier, RK Prichard - Pharmacogenetics and …, 2008 - journals.lww.com
Objectives We have found that in a laboratory strain of the nematode parasite of ruminants,
Haemonchus contortus, repeated ivermectin treatment, in vivo in sheep, selected against …