Oral administration is an appealing route of delivering cancer treatments. However, the
gastrointestinal tract is characterized by specific and efficient physical, chemical, and …

α-Lactalbumin (α-LA) is a small (Mr 14,200), acidic (pI 4–5), Ca2+-binding protein. α-LA is a
regulatory component of lactose synthase enzyme system functioning in the lactating …

In this report milk-derived exosomes have been investigated for oral delivery of the
chemotherapeutic drug paclitaxel (PAC) as an alternative to conventional iv therapy for …

Exosomes are extracellular microvesicles with a particle size of 30–100 nm and carry a
cargo of proteins, lipids, RNA, and DNA. Their properties of shuttling in-and-out of the cells …

Over the last two decades, berries and berry bioactives, particularly anthocyanins and their
aglycones anthocyanidins (Anthos) have demonstrated excellent anti-oxidant, anti …

ABSTRACT Alpha-lactalbumin (α-LA), a small milk calcium-binding globular protein, is
known to possess noticeable anticancer activity, which is determined by the ability of this …

Despite its prominent therapeutic efficacy, chemotherapy has raised serious concerns due to
the severe adverse effects and multidrug resistance evoked, which propels the search for …

Oleic acid (OA) is a monounsaturated fatty acid that upon binding to milk proteins, such as α-
lactalbumin and lactoferrin, forms potent complexes, which exert selective anti-tumor activity …

Some reports indicate that thymoquinone (TQ), the main constituent of Nigella sativa seeds,
is hepatoprotective. The aim of this study was to determine whether TQ is able to bind …

Chemotherapy side effects have long been a matter of great concern. Here we describe a
structurally stable self-assembled nanostructured lysozyme (snLYZ) synthesized using a …