Inflammatory and immune pathways in the pathogenesis of periodontal disease

A Cekici, A Kantarci, H Hasturk… - Periodontology …, 2014 - Wiley Online Library
The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints

GP Garlet - Journal of dental research, 2010 - journals.sagepub.com
Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Genetic susceptibility to periodontitis

ML Laine, W Crielaard, BG Loos - Periodontology 2000, 2012 - Wiley Online Library
In this systematic review, we explore and summarize the peer‐reviewed literature on
putative genetic risk factors for susceptibility to aggressive and chronic periodontitis. A …

Cytokine and cytokine receptor gene polymorphisms and their functionality

AJP Smith, SE Humphries - Cytokine & growth factor reviews, 2009 - Elsevier
Cytokines, signaling proteins produced by a variety of cell types, are essential for the
development and functioning of both innate and adaptive immune response. Cytokine gene …

Gene polymorphisms in chronic periodontitis

ML Laine, BG Loos, W Crielaard - International journal of …, 2010 - Wiley Online Library
We aimed to conduct a review of the literature for gene polymorphisms associated with
chronic periodontitis (CP) susceptibility. A comprehensive search of the literature in English …

Regulatory T cells attenuate experimental periodontitis progression in mice

GP Garlet, CR Cardoso, FS Mariano… - Journal of clinical …, 2010 - Wiley Online Library
Garlet GP, Cardoso CR, Mariano FS, Claudino M, de Assis GF, Campanelli AP, Ávila‐
Campos MJ, Silva JS. Regulatory T cells attenuate experimental periodontitis progression in …

[HTML][HTML] A systematic review and meta-analysis on multiple cytokine gene polymorphisms in the pathogenesis of periodontitis

X Liu, H Li - Frontiers in immunology, 2022 - frontiersin.org
Aim Periodontitis is an inflammatory disease that destroys both soft and hard periodontal
tissues. However, a complex periodontal cytokine network remains unclear. This systematic …

Immunomodulatory factors gene polymorphisms in chronic periodontitis: an overview

Z Heidari, B Moudi, H Mahmoudzadeh-Sagheb - BMC Oral Health, 2019 - Springer
Background Chronic periodontitis (CP), defines as destruction of the supporting tissues of
the teeth and resorption of the alveolar bone. It is widespread in human populations and …

The roles of genetic factors in Kawasaki disease: a systematic review and meta-analysis of genetic association studies

X Xie, X Shi, M Liu - Pediatric Cardiology, 2018 - Springer
This systematic review and meta-analysis aimed to better elucidate the roles of genetic
factors in Kawasaki disease (KD), and determine the potential genetic biomarkers of KD …

Effect of inflammation on cytokine levels and bone remodelling markers in peri-implant sulcus fluid: a preliminary report

GN Güncü, AC Akman, S Günday, N Yamalık, E Berker - Cytokine, 2012 - Elsevier
OBJECTIVES: Since ingredients of peri-implant sulcus fluid (PISF) may be related to the
bony structure surrounding dental implants, analyze of specific markers related to bone …