Sialic acids refer to a unique family of acidic sugars with a 9-carbon backbone that are
mostly found as terminal residues in glycan structures of glycoconjugates including both …

The importance of glycosylation (post-translational attachment of glycan residues to
proteins) in the context of neuroinflammation is only now beginning to be understood …

Glycosylation has been found to be altered in the brains of individuals with Alzheimer's
disease (AD). However, it is unknown which specific glycosylation-related pathways are …

Background Neuroinflammation is an underlying pathology of all neurological conditions,
the understanding of which is still being comprehended. A specific molecular pathway that …

Glycosylation is a common post-translational modification of brain proteins including cell
surface adhesion molecules, synaptic proteins, receptors and channels, as well as …

The attachment of carbohydrates to other macromolecules, such as proteins or lipids, is an
important regulatory mechanism termed glycosylation. One subtype of protein glycosylation …

Glycogen is a biologically essential macromolecule that is directly involved in multiple
human diseases. While its primary role in carbohydrate storage and energy metabolism in …

The importance of protein glycosylation in the biomedical field requires methods that not
only quantitate structures by their monosaccharide composition, but also resolve and identify …

Fucosylation, especially core fucosylation of N‐glycans catalyzed by α1‐6
fucosyltransferase (fucosyltransferase 8 or FUT8), plays an important role in regulating the …

Microglia are resident myeloid cells in the central nervous system (CNS) with a unique
developmental origin, playing essential roles in developing and maintaining the CNS …