Role of bile acids and bile acid receptors in metabolic regulation
The incidence of the metabolic syndrome has taken epidemic proportions in the past
decades, contributing to an increased risk of cardiovascular disease and diabetes. The …
decades, contributing to an increased risk of cardiovascular disease and diabetes. The …
Marine pharmacology in 2005–6: Marine compounds with anthelmintic, antibacterial, anticoagulant, antifungal, anti-inflammatory, antimalarial, antiprotozoal …
AMS Mayer, AD Rodríguez, RGS Berlinck… - … et Biophysica Acta (BBA …, 2009 - Elsevier
BACKGROUND: The review presents the 2005–2006 peer-reviewed marine pharmacology
literature, and follows a similar format to the authors' 1998–2004 reviews. The preclinical …
literature, and follows a similar format to the authors' 1998–2004 reviews. The preclinical …
Marine natural products
Covering: 2006. Previous review: Nat. Prod. Rep., 2007, 24, 31 This review covers the
literature published in 2006 for marine natural products, with 758 citations (534 for the …
literature published in 2006 for marine natural products, with 758 citations (534 for the …
[HTML][HTML] Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR
V Hiebl, A Ladurner, S Latkolik, VM Dirsch - Biotechnology advances, 2018 - Elsevier
Nuclear receptors (NRs) represent attractive targets for the treatment of metabolic syndrome-
related diseases. In addition, natural products are an interesting pool of potential ligands …
related diseases. In addition, natural products are an interesting pool of potential ligands …
Sesterterpenoids
L Wang, B Yang, XP Lin, XF Zhou, Y Liu - Natural product reports, 2013 - pubs.rsc.org
Covering: October 2006 to June 2012 This review, with 166 references, covers the literature
published on sesterterpenoids together with their relevant biological activities, source …
published on sesterterpenoids together with their relevant biological activities, source …
[HTML][HTML] Natural products targeting liver X receptors or farnesoid X receptor
J She, T Gu, X Pang, Y Liu, L Tang… - Frontiers in …, 2022 - frontiersin.org
Nuclear receptors (NRs) are a superfamily of transcription factors induced by ligands and
also function as integrators of hormonal and nutritional signals. Among NRs, the liver X …
also function as integrators of hormonal and nutritional signals. Among NRs, the liver X …
New marine natural products from sponges (Porifera) of the order Dictyoceratida (2001 to 2012); a promising source for drug discovery, exploration and future …
The discovery of new drugs can no longer rely primarily on terrestrial resources, as they
have been heavily exploited for over a century. During the last few decades marine sources …
have been heavily exploited for over a century. During the last few decades marine sources …
[HTML][HTML] Farnesoid X receptor: from structure to function and its pharmacology in liver fibrosis
C Ding, Z Wang, X Dou, Q Yang, Y Ning, S Kao… - Aging and …, 2024 - ncbi.nlm.nih.gov
The farnesoid X receptor (FXR), a ligand-activated transcription factor, plays a crucial role in
regulating bile acid metabolism within the enterohepatic circulation. Beyond its involvement …
regulating bile acid metabolism within the enterohepatic circulation. Beyond its involvement …
CXCR4 expression is elevated in TNBC patient derived samples and Z-guggulsterone abrogates tumor progression by targeting CXCL12/CXCR4 signaling axis in …
N Gupta, CD Mohan, MK Shanmugam, YY Jung… - Environmental …, 2023 - Elsevier
Environmental factors such as exposure to ionizing radiations, certain environmental
pollutants, and toxic chemicals are considered as risk factors in the development of breast …
pollutants, and toxic chemicals are considered as risk factors in the development of breast …
Scalarane sesterterpenoids
MA Gonzalez - Current Bioactive Compounds, 2010 - ingentaconnect.com
Scalarane Sesterterpenoids Page 1 178 Current Bioactive Compounds 2010, 6, 178-206
1573-4072/10 $55.00+.00 © 2010 Bentham Science Publishers Ltd. Scalarane …
1573-4072/10 $55.00+.00 © 2010 Bentham Science Publishers Ltd. Scalarane …