Corticotropin releasing hormone and proopiomelanocortin involvement in the cutaneous response to stress

A Slominski, J Wortsman, T Luger… - Physiological …, 2000 - journals.physiology.org
The skin is a known target organ for the proopiomelanocortin (POMC)-derived
neuropeptides α-melanocyte stimulating hormone (α-MSH), β-endorphin, and ACTH and …

Opioid and opiate immunoregulatory processes

GB Stefano, B Scharrer, EM Smith… - Critical Reviews™ in …, 2017 - dl.begellhouse.com
The discovery of the ability of the nervous system to communicate through" public" circuits
with other systems of the body is attributed to Ernst and Berta Scharrer, who described the …

Adrenal insufficiency occurring during septic shock: incidence, outcome, and relationship to peripheral cytokine levels

A Soni, GM Pepper, PM Wyrwinski, NE Ramirez… - The American journal of …, 1995 - Elsevier
PURPOSE: In patients with septic shock, to (1) determine the incidence of adrenal
insufficiency (AI),(2) observe the effects of glucocorticoid therapy on outcome in those with …

Associations between the neuroendocrine and immune systems

DA Weigent, JE Blalock - Journal of Leukocyte Biology, 1995 - Wiley Online Library
Organisms respond to infection with complex adaptations involving bidirectional
communication between the immune and neuroendocrine systems. The idea of intercellular …

Opiate-like substances in an invertebrate, an opiate receptor on invertebrate and human immunocytes, and a role in immunosuppression.

GB Stefano, A Digenis, S Spector… - Proceedings of the …, 1993 - National Acad Sciences
The presence of morphine-like and codeine-like substances was demonstrated in the pedal
ganglia, hemolymph, and mantle tissues of the mollusc Mytilus edulis. The pharmacological …

Detection of proopiomelanocortin-derived antigens in normal and pathologic human skin

A Slominski, J Wortsman… - The Journal of …, 1993 - translationalres.com
We investigated the presence of proopiomelanocortin (POMC) products in sections of skin
from normal subjects and patients with neoplastic and non-neoplastic cutaneous disorders …

In situ expression of corticotropin‐releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin

M Kono, H Nagata, S Umemura, S Kawana… - The FASEB …, 2001 - Wiley Online Library
Systemic stresses induce corticotropin‐releasing hormone (CRH) expression in
hypothalamus. CRH is released to the pituitary gland, where it stimulates …

Endogenous morphine and related opiates, a new class of chemical messengers

GB Stefano, B Scharrer - Advances in neuroimmunology, 1994 - Elsevier
1Multidisciplinary Center for the Study of Aging, Old Westbury Neuroscience Research
Institute, State University of New York at Old Westbury, Old Westbury, New York, 11568 …

Immunosuppression in the definitive and intermediate hosts of the human parasite Schistosoma mansoni by release of immunoactive neuropeptides.

O Duvaux-Miret, GB Stefano… - Proceedings of the …, 1992 - National Acad Sciences
Evidence supporting the concept that the parasitic trematode Schistosoma mansoni may
escape immune reactions from its vertebrate (man) or invertebrate (the freshwater snail …

Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormonea

TA Luger, T Scholzen, T Brzoska… - Annals of the New …, 1998 - Wiley Online Library
The capacity of the skin immune system to mount various types of immune responses is
largely dependent on their ability to release and respond to different signals provided by …