ATP-Sensitive potassium channels and their physiological and pathophysiological roles.
ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …
Endogenous opiates and behavior: 2016
RJ Bodnar - Peptides, 2018 - Elsevier
This paper is the thirty-ninth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2016 …
concerning the endogenous opioid system. It summarizes papers published during 2016 …
Ivermectin Exerts Anticonvulsant Effects Against Status Epilepticus Induced by Lithium-Pilocarpine in Rats via GABAA Receptor and Neuroinflammation Modulation: Possible …
Status epilepticus (SE) is a critical medical emergency marked by persistent or rapidly
repeating seizures, posing a threat to life. Using the lithium-pilocarpine-induced SE model …
repeating seizures, posing a threat to life. Using the lithium-pilocarpine-induced SE model …
Protective effect of minocycline on LPS-induced mitochondrial dysfunction and decreased seizure threshold through nitric oxide pathway
A Haj-Mirzaian, K Ramezanzadeh… - European journal of …, 2019 - Elsevier
Lipopolysaccharide (LPS) increases inflammatory cytokines of the brain and deregulates the
mitochondrial function, thus could increase the seizure susceptibility. Studies have shown …
mitochondrial function, thus could increase the seizure susceptibility. Studies have shown …
Possible interaction of opioidergic and nitrergic pathways in the anticonvulsant effect of ivermectin on pentylenetetrazole-induced clonic seizures in mice
S Jourian, M Rahimi, MA Manavi… - Neurochemical …, 2023 - Springer
Ivermectin (IVM) is an antiparasitic drug that primarily works by the activation of GABAA
receptors. The potential pharmacological pathways behind the anti-convulsant effect of IVM …
receptors. The potential pharmacological pathways behind the anti-convulsant effect of IVM …
Anticonvulsant effects of ivermectin on pentylenetetrazole-and maximal electroshock-induced seizures in mice: the role of GABAergic system and KATP channels
Introduction Ivermectin (IVM) is an antiparasitic medicine that exerts its function through
glutamate-gated chloride channels and GABA A receptors predominantly. There is paucity of …
glutamate-gated chloride channels and GABA A receptors predominantly. There is paucity of …
The Pharmacology of ATP-Sensitive K+ Channels (KATP)
Abstract ATP-sensitive K+ channels (KATP) are inwardly-rectifying potassium channels,
broadly expressed throughout the body. KATP is regulated by adenine nucleotides …
broadly expressed throughout the body. KATP is regulated by adenine nucleotides …
Anticonvulsant effect of melatonin through ATP‐sensitive channels in mice
Melatonin is a neurohormone secreted principally by the pineal gland. This molecule has
various pharmacological properties including improving immune system, prevent cancer …
various pharmacological properties including improving immune system, prevent cancer …
Involvement of nitrergic system in anticonvulsant effect of zolpidem in lithium-pilocarpine induced status epilepticus: evaluation of iNOS and COX-2 genes expression
This study aims to investigate the role of zolpidem in lithium-pilocarpine induced status
epilepticus (SE) and probable mechanisms involved in seizure threshold alteration. In the …
epilepticus (SE) and probable mechanisms involved in seizure threshold alteration. In the …
GABAA receptor, KATP channel and L-type Ca2+ channel is associated with facilitation effect of H2S on the baroreceptor reflex in spontaneous hypertensive rats
X Teng, H Li, H Xue, S Jin, L Xiao, Q Guo, Y Wu - Pharmacological Reports, 2019 - Elsevier
Background We aimed to investigate whether the facilitating effect of H 2 S on the
baroreceptor reflex is associated with the GABA A receptor, K ATP channel and L-type Ca …
baroreceptor reflex is associated with the GABA A receptor, K ATP channel and L-type Ca …