Anticancer potential of rosmarinic acid and its improved production through biotechnological interventions and functional genomics

MK Swamy, UR Sinniah, A Ghasemzadeh - Applied microbiology and …, 2018 - Springer
Rosmarinic acid (RA) is a highly valued natural phenolic compound that is very commonly
found in plants of the families Lamiaceae and Boraginaceae, including Coleus blumei …

Hairy root culture for the production of useful secondary metabolites

J Abraham, TD Thomas - Biotechnology and production of anti-cancer …, 2017 - Springer
Hairy root is induced when Agrobacterium rhizogenes, a naturally occurring gram-negative
soil bacterium, infects a plant that is susceptible to infection. During the infection process of …

Tailoring enhanced production of aervine in Aerva lanata (L.) Juss. Ex Schult by Agrobacterium rhizogenes-mediated hairy root cultures

S Boobalan, D Kamalanathan - Industrial Crops and Products, 2020 - Elsevier
Enhancement of secondary metabolites by means of hairy root culture is a potential method
for mass production of desired metabolites from in vitro plants. Accordingly, the aim of this …

Methyl‐β‐cyclodextrin and coronatine as new elicitors of tropane alkaloid biosynthesis in Atropa acuminata and Atropa belladonna hairy root cultures

F Fattahi, A Shojaeiyan, J Palazon… - Physiologia …, 2021 - Wiley Online Library
Hyoscyamine (HYO) and scopolamine (SCO) are tropane alkaloids acting as anticholinergic
factors on the parasympathetic nervous system in humans and are produced by …

Improving diosgenin production and its biosynthesis in Trigonella foenum-graecum L. hairy root cultures

F Zolfaghari, S Rashidi-Monfared, A Moieni… - Industrial crops and …, 2020 - Elsevier
Induction of hairy roots stemmed from Agrobacterium rhizogenes transformation, is a key
step to reach mass production of secondary metabolites in medicinal plants. Accordingly …

Enhancement of Celastrol compound by silver nanoparticles and acetosyringone in Celastrus paniculatus Willd. through adventitious and hairy root culture

AK Moola, T Senthil Kumar… - Journal of plant …, 2022 - Springer
Celastrus paniculatus Willd., an important medicinal plant for the treatment of
neurodegenerative diseases is at risk of extinction due to destructive harvesting by …

Elite hairy roots of Raphanus sativus (L.) as a source of antioxidants and flavonoids

M Balasubramanian, M Anbumegala, R Surendran… - 3 Biotech, 2018 - Springer
An efficient protocol for hairy root induction in radish was established by optimizing several
parameters that affect the efficiency of Agrobacterium rhizogenes-mediated transformations …

Establishment of Agrobacterium rhizogenes-mediated hairy root transformation of Crocus sativus L.

S Sharma, Y Singh, PK Verma, J Vakhlu - 3 Biotech, 2021 - Springer
Efficient transformation system for genetic improvement is essential in Crocus sativus, as it
lacks sexual reproduction. This is the first report wherein an efficient protocol is developed …

Hairy root induction in hybrid poplar (Populus tremula × Populus alba) for sustainable growth and specialized metabolites production with antioxidant activities

M Laffon, M Bruat, F Chefdor, C Colas, S Heng… - Plant Cell, Tissue and …, 2024 - Springer
Rhizobium rhizogenes mediated genetic transformation is a promising biotechnological tool
to obtain specialized metabolites having valuable biological activities. The present study …

Preliminary phytochemical analysis and evaluation of the biological activity of Leonotis nepetifolia (L.) r. br transformed roots extracts obtained through rhizobium …

T Kowalczyk, A Merecz-Sadowska, P Rijo, VMS Isca… - Cells, 2021 - mdpi.com
According to the present knowledge, this is the first report on establishing transformed root
cultures of Leonotis nepetifolia after Rhizobium rhizogenes-mediated transformation. The …