Recent advances in the mechanisms of neuroinflammation and their roles in neurodegeneration

R Niranjan - Neurochemistry international, 2018 - Elsevier
Neuroinflammation is associated with the pathogenesis of many neurological disorders
including Parkinson's disease, Alzheimer's disease, Amyotrophic lateral sclerosis and …

Dysregulation of inflammasome activation in glioma

JM Sim, JM Park, JS Moon, J Lim - Cell Communication and Signaling, 2023 - Springer
Gliomas are the most common brain tumors characterized by complicated heterogeneity.
The genetic, molecular, and histological pathology of gliomas is characterized by high neuro …

In vitro evaluation of the synergistic antioxidant and anti-inflammatory activities of the combined extracts from Malaysian Ganoderma lucidum and Egyptian Chlorella …

MM Abu-Serie, NH Habashy, WE Attia - BMC Complementary and …, 2018 - Springer
Background Since oxidative stress and inflammation are two linked factors in the
pathogenesis of several human diseases. Thus identification of effective treatment is of great …

The effects of incensole acetate on neuro-inflammation, brain-derived neurotrophic factor and memory impairment induced by lipopolysaccharide in rats

N Marefati, F Beheshti, F Vafaee, M Barabadi… - Neurochemical …, 2021 - Springer
Incensole acetate (IA) is a major component of Boswellia serrata resin that has been shown
to have anti-inflammatory, anti-oxidant and neuroprotective properties. The present study …

Inhibition of cyclooxygenase-2 (COX-2) initiates autophagy and potentiates MPTP-induced autophagic cell death of human neuroblastoma cells, SH-SY5Y: an inside …

R Niranjan, KP Mishra, AK Thakur - Molecular neurobiology, 2018 - Springer
Abstract Cyclooxygenase-2 or COX-2 has been known to be crucial for Parkinson's disease
(PD) pathogenesis; however, its exact role is still not known. We first time report that …

Protection of streptozotocin induced insulin receptor dysfunction, neuroinflammation and amyloidogenesis in astrocytes by insulin

N Rajasekar, S Dwivedi, C Nath, K Hanif, R Shukla - Neuropharmacology, 2014 - Elsevier
Impaired insulin signaling, amyloid pathology and neuroinflammation are closely associated
with neurodegenerative disorder like Alzheimer's disease (AD). Our earlier studies showed …

Lipopolysaccharide-induced matrix metalloproteinase-9 expression associated with cell migration in rat brain astrocytes

CC Yang, CC Lin, LD Hsiao, JM Kuo… - International Journal of …, 2019 - mdpi.com
Neuroinflammation is a landmark of neuroinflammatory and neurodegenerative diseases.
Matrix metalloproteinase (MMP)-9, one member of MMPs, has been shown to contribute to …

Matrix metalloproteinases in the pathogenesis of dengue viral disease: involvement of immune system and newer therapeutic strategies

R Niranjan, S Kishor, A Kumar - Journal of Medical Virology, 2021 - Wiley Online Library
Globally, the burden due to dengue infection is increasing with a recent estimate of 96
million progressing to the disease every year. Dengue pathogenesis and the factors …

[HTML][HTML] TLR4 interaction with LPS in glioma CD133+ cancer stem cells induces cell proliferation, resistance to chemotherapy and evasion from cytotoxic T lymphocyte …

F Che, J Yin, Y Quan, X Xie, X Heng, Y Du, L Wang - Oncotarget, 2017 - ncbi.nlm.nih.gov
Despite advances in treatment modalities, 5-year survival among glioma patients remains
poor. Glioma cancer stem cells (CSCs) exhibit high tumorigenic activity and are associated …

Inhibitory effect of memantine on streptozotocin-induced insulin receptor dysfunction, neuroinflammation, amyloidogenesis, and neurotrophic factor decline in …

N Rajasekar, C Nath, K Hanif, R Shukla - Molecular neurobiology, 2016 - Springer
Our earlier studies showed that insulin receptor (IR) dysfunction along with
neuroinflammation and amyloidogenesis played a major role in streptozotocin (STZ) …