Toward an evolutionarily appropriate null model: jointly inferring demography and purifying selection

P Johri, B Charlesworth, JD Jensen - Genetics, 2020 - academic.oup.com
The relative evolutionary roles of adaptive and non-adaptive processes remain a central
question in population genetics. Resolution of this debate has been difficult as an …

Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA …

M Kapun, MG Barrón, F Staubach… - Molecular Biology …, 2020 - academic.oup.com
Genetic variation is the fuel of evolution, with standing genetic variation especially important
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …

[PDF][PDF] An ancestral balanced inversion polymorphism confers global adaptation

M Kapun, ED Mitchell, TJ Kawecki… - … Biology and Evolution, 2023 - academic.oup.com
Since the pioneering work of Dobzhansky in the 1930s and 1940s, many chromosomal
inversions have been identified, but how they contribute to adaptation remains poorly …

Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans

Y Wang, P McNeil, R Abdulazeez, M Pascual… - Genome …, 2023 - genome.cshlp.org
The rates of mutation, recombination, and transposition are core parameters in models of
evolution. They impact genetic diversity, responses to ongoing selection, and levels of …

Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster

A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023 - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …

Recurrent Collection of Drosophila melanogaster from Wild African Environments and Genomic Insights into Species History

QD Sprengelmeyer, S Mansourian… - Molecular biology …, 2020 - academic.oup.com
A long-standing enigma concerns the geographic and ecological origins of the intensively
studied vinegar fly, Drosophila melanogaster. This globally distributed human commensal is …

Demographic History of the Human Commensal Drosophila melanogaster

JR Arguello, S Laurent, AG Clark - Genome biology and …, 2019 - academic.oup.com
The cohabitation of Drosophila melanogaster with humans is nearly ubiquitous. Though it
has been well established that this fly species originated in sub-Saharan Africa, and only …

Epistatic selection on a selfish Segregation Distorter supergene–drive, recombination, and genetic load

B Navarro-Dominguez, CH Chang, CL Brand… - Elife, 2022 - elifesciences.org
Meiotic drive supergenes are complexes of alleles at linked loci that together subvert
Mendelian segregation resulting in preferential transmission. In males, the most common …

Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation in Drosophila

HE Machado, AO Bergland, R Taylor, S Tilk… - BioRxiv, 2018 - biorxiv.org
To advance our understanding of adaptation to temporally varying selection pressures, we
identified signatures of seasonal adaptation occurring in parallel among Drosophila …

The evolutionary arms race between transposable elements and piRNAs in Drosophila melanogaster

S Luo, H Zhang, Y Duan, X Yao, AG Clark… - BMC Evolutionary Biology, 2020 - Springer
Abstract Background The piwi-interacting RNAs (piRNAs) are small non-coding RNAs that
specifically repress transposable elements (TEs) in the germline of Drosophila. Despite our …