Toward an evolutionarily appropriate null model: jointly inferring demography and purifying selection
The relative evolutionary roles of adaptive and non-adaptive processes remain a central
question in population genetics. Resolution of this debate has been difficult as an …
question in population genetics. Resolution of this debate has been difficult as an …
Genomic Analysis of European Drosophila melanogaster Populations Reveals Longitudinal Structure, Continent-Wide Selection, and Previously Unknown DNA …
M Kapun, MG Barrón, F Staubach… - Molecular Biology …, 2020 - academic.oup.com
Genetic variation is the fuel of evolution, with standing genetic variation especially important
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …
for short-term evolution and local adaptation. To date, studies of spatiotemporal patterns of …
[PDF][PDF] An ancestral balanced inversion polymorphism confers global adaptation
Since the pioneering work of Dobzhansky in the 1930s and 1940s, many chromosomal
inversions have been identified, but how they contribute to adaptation remains poorly …
inversions have been identified, but how they contribute to adaptation remains poorly …
Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans
The rates of mutation, recombination, and transposition are core parameters in models of
evolution. They impact genetic diversity, responses to ongoing selection, and levels of …
evolution. They impact genetic diversity, responses to ongoing selection, and levels of …
Population genomics reveals mechanisms and dynamics of de novo expressed open reading frame emergence in Drosophila melanogaster
A Grandchamp, L Kühl, M Lebherz… - Genome …, 2023 - genome.cshlp.org
Novel genes are essential for evolutionary innovations and differ substantially even between
closely related species. Recently, multiple studies across many taxa showed that some …
closely related species. Recently, multiple studies across many taxa showed that some …
Recurrent Collection of Drosophila melanogaster from Wild African Environments and Genomic Insights into Species History
QD Sprengelmeyer, S Mansourian… - Molecular biology …, 2020 - academic.oup.com
A long-standing enigma concerns the geographic and ecological origins of the intensively
studied vinegar fly, Drosophila melanogaster. This globally distributed human commensal is …
studied vinegar fly, Drosophila melanogaster. This globally distributed human commensal is …
Demographic History of the Human Commensal Drosophila melanogaster
The cohabitation of Drosophila melanogaster with humans is nearly ubiquitous. Though it
has been well established that this fly species originated in sub-Saharan Africa, and only …
has been well established that this fly species originated in sub-Saharan Africa, and only …
Epistatic selection on a selfish Segregation Distorter supergene–drive, recombination, and genetic load
Meiotic drive supergenes are complexes of alleles at linked loci that together subvert
Mendelian segregation resulting in preferential transmission. In males, the most common …
Mendelian segregation resulting in preferential transmission. In males, the most common …
Broad geographic sampling reveals predictable, pervasive, and strong seasonal adaptation in Drosophila
To advance our understanding of adaptation to temporally varying selection pressures, we
identified signatures of seasonal adaptation occurring in parallel among Drosophila …
identified signatures of seasonal adaptation occurring in parallel among Drosophila …
The evolutionary arms race between transposable elements and piRNAs in Drosophila melanogaster
Abstract Background The piwi-interacting RNAs (piRNAs) are small non-coding RNAs that
specifically repress transposable elements (TEs) in the germline of Drosophila. Despite our …
specifically repress transposable elements (TEs) in the germline of Drosophila. Despite our …