Excessive alcohol consumption is a global healthcare problem. The liver sustains the
greatest degree of tissue injury by heavy drinking because it is the primary site of ethanol …

Simple Summary A large number of studies report that medicinal herbs and many food
ingredients protect against the development of liver disease because they possess …

As one of the bicyclic metabolic pathways of one-carbon metabolism, methionine
metabolism is the pivot linking the folate cycle to the transsulfuration pathway. In addition to …

Excessive alcohol consumption is a global healthcare problem with enormous social,
economic, and clinical consequences. While chronic, heavy alcohol consumption causes …

The mechanisms of immune dysfunction in alcohol-associated liver disease (ALD) have
garnered growing research interest in recent times. Alcohol-mediated immune dysfunction …

Elimination of hepatitis C virus (HCV) without the need for medical intervention, known as
spontaneous clearance (SC), occurs at a significantly lower rate than in the case of hepatitis …

In liver steatosis (ie fatty liver), hepatocytes accumulate many large neutral lipid storage
organelles known as lipid droplets (LDs). LDs are important in the maintenance of energy …

Abstract Acetaldehyde dehydrogenase 2 (ALDH2) is the key enzyme responsible for
metabolism of the alcohol metabolite acetaldehyde in the liver. In addition to conversion of …

Common liver tissue damage is mainly due to the accumulation of toxic aldehydes in lipid
peroxidation under oxidative stress. Cumulative toxic aldehydes in the liver can be …

Abstract Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme of alcohol metabolism and it
is involved in the cellular mechanism of alcohol liver disease. ALDH2 gene mutations exist …