[HTML][HTML] Liquid Biopsy in Head and Neck Cancer: Its Present State and Future Role in Africa

DO Temilola, HA Adeola, J Grobbelaar, M Chetty - Cells, 2023 - mdpi.com
The rising mortality and morbidity rate of head and neck cancer (HNC) in Africa has been
attributed to factors such as the poor state of health infrastructures, genetics, and late …

DNA repair genes XPC, XPD, XRCC1, and XRCC3 are associated with risk and survival of squamous cell carcinoma of the head and neck

L Farnebo, A Stjernström, M Fredrikson, A Ansell… - DNA repair, 2015 - Elsevier
Head and neck squamous cell carcinomas (HNSCC) are a heterogenous group of tumors
with a high rate of early recurrences, second primary tumors, and mortality. Despite …

Increased expression of ERCC2 gene in head and neck cancer is associated with aggressive tumors: a systematic review and case-control study

M Zafeer, I Mahjabeen… - The International journal …, 2016 - journals.sagepub.com
Introduction The excision repair cross-complementation group 2 (ERCC2) ATP-dependent
helicase is an essential member of the DNA repair pathway. It has been observed to be …

[HTML][HTML] Exposure to volatile anaesthetics is not followed by a massive induction of single-strand DNA breaks in operation theatre personnel

K Szyfter, I Stachecki, M Kostrzewska-Poczekaj… - Journal of applied …, 2016 - Springer
Volatile anaesthetics such as halothane, isoflurane and others were expected to produce a
health challenge for operation room personnel because of prolonged occupational …

Combined effect of tobacco and DNA repair genes polymorphisms of XRCC1 and XRCC2 influence high risk of head and neck squamous cell carcinoma in …

JH Choudhury, B Choudhury, S Kundu, SK Ghosh - Medical Oncology, 2014 - Springer
Tobacco consumption in various forms is one of the major risk factor for the development of
head and neck squamous cell carcinoma. Polymorphisms in XRCC1 and XRCC2 genes …

Clinicopathological significance of SNPs in RAD51 and XRCC3 in oral and oropharyngeal carcinomas

EM Santos, HBP Santos, FR de Matos… - Oral …, 2019 - Wiley Online Library
Background This study investigated the influence of single nucleotide polymorphisms (SNP)
in RAD51 and XRCC3 on susceptibility to oral and oropharyngeal squamous cell …

The association between the XRCC1 Arg399Gln polymorphism and the risk of head and neck cancer: an updated meta-analysis including 14586 subjects

S Xia, S Wu, M Wang - Technology in cancer research & …, 2021 - journals.sagepub.com
Background: Accumulated evidence shows that DNA repair gene X-ray repair cross
complementing group 1 (XRCC1) may determine individual susceptibility to head and neck …

Association between polymorphisms in genes related to DNA base-excision repair with risk and prognosis of oropharyngeal squamous cell carcinoma

EFD Costa, ES Santos, VT Liutti, F Leal… - Journal of cancer …, 2016 - Springer
Purpose We examined the influence of OGG1 c. 977C> G (rs1052133), APEX1 c. 444T> G
(rs1130409), XRCC1 c.-77T> C (rs3213245), c. 580C> T (rs1799782), c. 839G> A (rs25489) …

Single nucleotide polymorphisms in DNA repair genes and the risk of laryngeal cancer: a meta-analysis

F Li, J Wang, M Chen - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Laryngeal cancer is the most common type of head and neck cancer with poor prognosis
and high relapse rate. Several genes involved in DNA repair pathways have been identified …

Genetic polymorphisms in DNA repair genes XRCC1 and 3 are associated with increased risk of breast cancer in Bangladeshi population

NR Howlader, MM Rahman, MA Hossain… - Breast Cancer Research …, 2020 - Springer
Background Genetic polymorphisms in DNA repair genes, XRCC1 (Arg399Gln) and XRCC3
(Thr241Met), may affect their DNA repair capacity leading to individual variation in breast …