Glial tiling in the insect nervous system

N Pogodalla, B Winkler, C Klämbt - Frontiers in Cellular …, 2022 - frontiersin.org
The Drosophila nervous system comprises a small number of well characterized glial cell
classes. The outer surface of the central nervous system (CNS) is protected by a glial …

JNK signaling in pioneer neurons organizes ventral nerve cord architecture in Drosophila embryos

K Karkali, TE Saunders, G Panayotou… - Nature …, 2023 - nature.com
Abstract Morphogenesis of the Central Nervous System (CNS) is a complex process that
obeys precise architectural rules. Yet, the mechanisms dictating these rules remain …

Signaling Pathways Controlling Axonal Wrapping in Drosophila

M Baldenius, S Kautzmann, S Nanda, C Klämbt - Cells, 2023 - mdpi.com
The rapid transmission of action potentials is an important ability that enables efficient
communication within the nervous system. Glial cells influence conduction velocity along …

An axon-pathfinding mechanism preserves epithelial tissue integrity

C Cammarota, TM Finegan, TJ Wilson, S Yang… - Current Biology, 2020 - cell.com
Epithelial tissues form the boundaries of organs, where they perform a range of functions,
including secretion, absorption, and protection. These tissues are commonly composed of …

Acute manipulation and real-time visualization of membrane trafficking and exocytosis in Drosophila

J Glashauser, C Camelo, M Hollmann, W Backer… - Developmental Cell, 2023 - cell.com
Intracellular trafficking of secretory proteins plays key roles in animal development and
physiology, but so far, tools for investigating the dynamics of membrane trafficking have …

A neural cell adhesion molecule from oyster Crassostrea gigas: Molecular identification and immune functional characterization

X Qiao, C Liu, W Wang, C Yang, M Li, Q Yi… - International Journal of …, 2023 - Elsevier
Neural cell adhesion molecules (NCAMs) are large cell-surface glycoproteins playing
important roles in cell-cell and cell-extracellular matrix interactions in nervous system …

Exocyst-mediated membrane trafficking of the lissencephaly-associated ECM receptor dystroglycan is required for proper brain compartmentalization

AS Yatsenko, MM Kucherenko, Y Xie, H Urlaub… - Elife, 2021 - elifesciences.org
To assemble a brain, differentiating neurons must make proper connections and establish
specialized brain compartments. Abnormal levels of cell adhesion molecules disrupt these …

Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in …

WJ Tan, HR Hawley, SJ Wilson, HL Fitzsimons - BMC biology, 2024 - Springer
Background Dysregulation of nucleocytoplasmic shuttling of histone deacetylase 4 (HDAC4)
is associated with several neurodevelopmental and neurodegenerative disorders …

Fas2EB112: a tale of two chromosomes

TM Finegan, C Cammarota… - G3: Genes …, 2024 - academic.oup.com
The cell–cell adhesion molecule Fasciclin II (Fas2) has long been studied for its
evolutionarily conserved role in axon guidance. It is also expressed in the follicular …

Fasciclin 2 engages EGFR in an auto-stimulatory loop to promote imaginal disc cell proliferation in Drosophila

E Velasquez, JA Gomez-Sanchez, E Donier… - PLoS …, 2022 - journals.plos.org
How cell to cell interactions control local tissue growth to attain a species-specific organ size
is a central question in developmental biology. The Drosophila Neural Cell Adhesion …