Conspectus More than 170 different types of chemical modifications have been identified on
diverse types of RNA, collectively known as the epitranscriptome. Among them, N 6 …

Metabolic reactions within cells occur in various isolated compartments with or without
borders, the latter being known as membrane-less organelles (MLOs). The MLOs show …

A common mRNA modification is 5-methylcytosine (m 5 C), whose role in gene-transcript
processing and cancer remains unclear. Here, we identify serine/arginine-rich splicing factor …

methylcytosine (m 5 C) is a prevalent RNA modification crucial for gene expression
regulation. However, accurate and sensitive m 5 C sites identification remains challenging …

Liquid–liquid phase separation (LLPS) is a crucial process for the formation of biomolecular
condensates such as coacervate droplets, P-bodies and stress granules, which play critical …

RNA-binding proteins (RBPs) fine-tune gene expression by modulating RNA stability,
translation, and degradation. RBPs are involved in the development of endometrial cancer …

RNA methylation modifications influence gene expression, and disruptions of these
processes are often associated with various human diseases. The common RNA …

A large number of mRNAs of maternal origin are produced during oogenesis and deposited
in the oocyte. Since transcription stops at the onset of meiosis during oogenesis and does …

Phase separation is a critical mechanism for partitioning cellular functions by specific
aggregation of biological macromolecules. Recent studies have found that phase separation …

Adipose tissue plays a crucial role in maintaining energy balance, regulating hormones, and
promoting metabolic health. To address disorders related to obesity and develop effective …