Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update

R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Fibromyalgia: a critical and comprehensive review

AT Borchers, ME Gershwin - Clinical reviews in allergy & immunology, 2015 - Springer
Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise
classification. It is often considered as part of the global overview of functional somatic …

[HTML][HTML] Diagnostic challenges and management of fibromyalgia

AG Qureshi, SK Jha, J Iskander, C Avanthika, S Jhaveri… - Cureus, 2021 - ncbi.nlm.nih.gov
Abstract The World Health Organization regards chronic pain to be a public health concern.
In clinical medicine, fibromyalgia (FM) is the most prevalent chronic widespread pain …

Endogenous opiates and behavior: 2014

RJ Bodnar - Peptides, 2016 - Elsevier
This paper is the thirty-seventh consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2014 …

Novel diagnostic and prognostic methods for disc degeneration and low back pain

D Samartzis, A Borthakur, I Belfer, C Bow, JC Lotz… - The spine journal, 2015 - Elsevier
Low back pain (LBP) is the world's leading debilitating condition [1]. It is estimated that 80%
of the general population in the United States will develop LBP at one point in time [2],[3] …

Fibromyalgia: a review of related polymorphisms and clinical relevance

LP Janssen, LF Medeiros, ADE Souza… - Anais da Academia …, 2021 - SciELO Brasil
Fibromyalgia (FM) is a chronic pain syndrome that affects the central nervous system and
generates disability, which is characterized by generalized pain, fatigue, and functional …

[HTML][HTML] Central sensitization in opioid use disorder: a novel application of the American College of Rheumatology Fibromyalgia Survey Criteria

OT Hall, J Teater, KM Rood, KL Phan, DJ Clauw - PAIN reports, 2022 - journals.lww.com
Methods: Participants with OUD (n= 141) were recruited from an academic addiction
treatment center in Columbus, Ohio. An established surrogate measure of CS, the American …

[PDF][PDF] The relevance of the OPRM1 118A> G genetic variant for opioid requirement in pain treatment: a meta-analysis

X Zhang, Y Liang, N Zhang, Y Yan, S Liu… - Pain …, 2019 - painphysicianjournal.com
Background: There is obvious difference in individual response to opioids. Many studies
have examined the correlation between the μ-opioid receptor 1 (OPRM1) 118A> G genetic …

Polymorphisms of the μ‐opioid receptor gene influence cerebral pain processing in fibromyalgia

I Ellerbrock, A Sandström, J Tour… - … journal of pain, 2021 - Wiley Online Library
Background Dysregulation of the μ‐opioid receptor has been reported in fibromyalgia (FM)
and was linked to pain severity. Here, we investigated the effect of the functional genetic …

Association of OPRM1 rs1799971, HTR1B rs6296 and COMT rs4680 polymorphisms with clinical phenotype among women with fibromyalgia

C Fernández-de-Las-Peñas, S Ambite-Quesada… - Scientific Reports, 2024 - nature.com
To investigate the association between three selected pain polymorphisms and clinical,
functional, sensory-related, psychophysical, psychological or cognitive variables in a sample …